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Oxidative Cleavage of Alkenes: Ozonolysis

Oxidative Cleavage of Alkenes: Ozonolysis

In ozonolysis, ozone is used to cleave a carbon–carbon double bond to form aldehydes and ketones, or carboxylic acids, depending on the work-up.
Ozone is a symmetrical bent molecule stabilized by a resonance structure.

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Related Experiment Video

Updated: Jan 13, 2026

Generation of a Chronic Obstructive Pulmonary Disease Model in Mice by Repeated Ozone Exposure

Generation of a Chronic Obstructive Pulmonary Disease Model in Mice by Repeated Ozone Exposure

Published on: August 25, 2017

Ozone-Induced Encephalopathy Following Subcutaneous Ozone Injection: A Case Report.

Cristiano Gante¹, Luís Dias¹

¹Internal Medicine, Hospital de São José, Unidade Local de Saúde de São José, Lisbon, PRT.

|January 6, 2026

Summary

Ozone therapy can cause severe neurological complications like acute encephalopathy, even after subcutaneous injections. This case highlights the risks of improper ozone administration, emphasizing the need for safety standards.

Area of Science:

Neurology
Alternative Medicine
Medical Safety

Background:

Ozone therapy is increasingly popular for various conditions, but scientific evidence for its safety and efficacy is limited.

Keywords:

altered mental state alternative medical therapies emergency department encephalopathy ozone therapy

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Severe neurological complications from ozone therapy are rare but possible.

The case involves a previously healthy individual experiencing adverse effects from an alternative treatment.