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Updated: Jan 13, 2026
A Real-World High-Intensity Interval Training Protocol for Cardiorespiratory Fitness Improvement
Published on: February 22, 2022
High-Intensity Interval Training Enhances Cardiovascular and Functional Outcomes Compared With Moderate-Intensity
1Cardiopulmonary Therapy Unit, Department of Rehabilitation Medicine, Bundang Jesaeng Hospital, Seongnam, Korea.
Objective:
To compare the effects of high-intensity interval training (HIIT) and moderate-intensity continuous training (MICT) on cardiovascular function, gait ability, and hematological variables in chronic stroke survivors.
Methods:
Twenty-nine higher-functioning, ambulatory chronic stroke survivors were randomized to HIIT (n=15) or MICT (n=14). Participants underwent supervised training three times weekly for six weeks, consisting of 30 minutes conventional therapy followed by 40 minutes aerobic exercise (HIIT: six 1-minute high-intensity intervals at 80%-100% maximum heart rate (HRmax) with 4-minute active recovery; MICT: continuous exercise at 60%-80% HRmax). Outcomes included cardiovascular function (maximal oxygen uptake [VO2max], HRmax, walking heart rate), gait (10-Meter Walk Test, Timed Up and Go test, 6-Minute Walk Test), and lipid profiles (low-density lipoprotein, high-density lipoprotein, triglycerides).
Results:
In this higher-functioning cohort (n=29), HIIT showed significantly greater improvements than MICT in VO2max (F=40.574, p=0.001), HR_max (F=24.661, p=0.001), walking heart rate (F=11.277, p=0.002), 10-Meter Walk Test (F=20.865, p=0.001), Timed Up and Go test (F=12.317, p=0.002), and 6-Minute Walk Test (F=9.742, p=0.004). Lipid profiles improved significantly within the HIIT group only (p<0.05), no between-group differences were observed.
Conclusion:
In higher-functioning chronic stroke survivors, HIIT was superior to MICT for cardiovascular fitness and functional mobility under a matched exposure; lipid changes occurred within HIIT only without between-group effects. These findings support incorporating HIIT into stroke rehabilitation programs to enhance recovery outcomes.
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