Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Imaging Studies II: Positron Emission Tomography and Scintigraphy01:25

Imaging Studies II: Positron Emission Tomography and Scintigraphy

493
Positron Emission Tomography (PET) is a medical imaging technique that provides crucial insights into the body's physiological functions at a molecular level. It is an indispensable resource for diagnosing, staging, and monitoring various illnesses, notably cancer, neurological disorders, and cardiovascular conditions.
Fundamental Principles of PET
493
Radiological Investigation III: Pulmonary Angiogram and PET Scan01:13

Radiological Investigation III: Pulmonary Angiogram and PET Scan

400
Radiological investigations are paramount in the diagnosis and management of various pulmonary diseases. Two essential investigations are the Pulmonary Angiogram and the Positron Emission Tomography (PET) Scan.
Pulmonary Angiogram
A Pulmonary Angiogram is an invasive procedure involving injecting a contrast medium through a catheter threaded into the pulmonary artery or the right side of the heart to visualize the pulmonary vasculature. Computed Tomography (CT) scans have mainly replaced this...
400
Imaging Studies for Cardiovascular System III: X-Ray01:20

Imaging Studies for Cardiovascular System III: X-Ray

462
The most common cardiovascular diagnostic test is an X-ray. It produces images of the heart, blood vessels, and adjacent structures.
Definition and Purpose
An X-ray, or radiograph, is a non-invasive method that uses ionizing radiation to take images of internal structures. It is mainly used in cardiac imaging to examine the heart, lungs, and major blood vessels, aiming to identify abnormalities in the heart's size, shape, and position, such as heart failure, congenital defects, and vascular...
462
X-ray Imaging01:24

X-ray Imaging

9.8K
German physicist Wilhelm Röntgen (1845–1923) was experimenting with electrical current when he discovered that a mysterious and invisible "ray" would pass through his flesh but leave an outline of his bones on a screen coated with a metal compound. In 1895, Röntgen made the first durable record of the internal parts of a living human: an "X-ray" image (as it came to be called) of his wife’s hand. Scientists worldwide quickly began their own experiments with...
9.8K
Positron Emission Tomography01:29

Positron Emission Tomography

6.9K
Positron emission tomography (PET) is a medical imaging technique involving radiopharmaceuticals — substances that emit short-lived radiation. Although the first PET scanner was introduced in 1961, it took 15 more years before radiopharmaceuticals were combined with the technique and revolutionized its potential.
One of the main requirements of a PET scan is a positron-emitting radioisotope, which is produced in a cyclotron and then attached to a substance used by the part of the body...
6.9K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Cleft team strategy and caries experience in patients with a cleft lip and/or palate, a multicentre study.

European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry·2026
Same author

Sterile Versus Non-Sterile Gloves in Dental Extractions: A Systematic Review and Meta-Analysis.

Craniomaxillofacial trauma & reconstruction·2026
Same author

Association Between Helmet Use and the Frequency of Maxillofacial Injuries After Bicycle- or Scooter-Related Accidents in Children.

Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons·2026
Same author

Facial asymmetry in syndromic craniosynostosis patients undergoing midface surgery compared to a large general population.

Journal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery·2025
Same author

Post-traumatic and iatrogenic silent sinus syndrome: a case series.

Oral and maxillofacial surgery·2025
Same author

Comparison of a third surgical protocol for the treatment of unilateral cleft lip and palate: a multidisciplinary systematic review and meta-analysis.

International journal of oral and maxillofacial surgery·2025

Related Experiment Video

Updated: Jan 13, 2026

Detection of Residual Donor Erythroid Progenitor Cells after Hematopoietic Stem Cell Transplantation for Patients with Hemoglobinopathies
11:59

Detection of Residual Donor Erythroid Progenitor Cells after Hematopoietic Stem Cell Transplantation for Patients with Hemoglobinopathies

Published on: September 6, 2017

7.8K

[Beta thalassaemia: a surprising radiological image].

S Ombashi1, M Wevers1, J C G Wagemans1

  • 1From the Department of Oral Diseases, Maxillofacial Surgery/Special Dentistry Outpatient Clinic at Erasmus Medical Centre, Rotterdam.

Nederlands Tijdschrift Voor Tandheelkunde
|January 6, 2026
PubMed
Summary

Thalassaemia, a genetic blood disorder, causes haemolytic anaemia due to defective haemoglobin chain synthesis. This leads to bone changes and organ hypertrophy, but typically requires no specific maxillofacial or dental treatment.

More Related Videos

In Vivo Imaging and Tracking of Technetium-99m Labeled Bone Marrow Mesenchymal Stem Cells in Equine Tendinopathy
07:52

In Vivo Imaging and Tracking of Technetium-99m Labeled Bone Marrow Mesenchymal Stem Cells in Equine Tendinopathy

Published on: December 9, 2015

10.1K
Portable Thermographic Screening for Detection of Acute Wallenberg's Syndrome
05:12

Portable Thermographic Screening for Detection of Acute Wallenberg's Syndrome

Published on: September 19, 2019

6.9K

Related Experiment Videos

Last Updated: Jan 13, 2026

Detection of Residual Donor Erythroid Progenitor Cells after Hematopoietic Stem Cell Transplantation for Patients with Hemoglobinopathies
11:59

Detection of Residual Donor Erythroid Progenitor Cells after Hematopoietic Stem Cell Transplantation for Patients with Hemoglobinopathies

Published on: September 6, 2017

7.8K
In Vivo Imaging and Tracking of Technetium-99m Labeled Bone Marrow Mesenchymal Stem Cells in Equine Tendinopathy
07:52

In Vivo Imaging and Tracking of Technetium-99m Labeled Bone Marrow Mesenchymal Stem Cells in Equine Tendinopathy

Published on: December 9, 2015

10.1K
Portable Thermographic Screening for Detection of Acute Wallenberg's Syndrome
05:12

Portable Thermographic Screening for Detection of Acute Wallenberg's Syndrome

Published on: September 19, 2019

6.9K

Area of Science:

  • Hematology
  • Genetics
  • Pathology

Background:

  • Thalassaemia results from impaired alpha or beta-globin chain synthesis, crucial for haemoglobin formation.
  • The primary clinical manifestation is haemolytic anaemia, characterized by premature red blood cell destruction.
  • Chronic anaemia stimulates erythropoiesis, leading to secondary effects like bone deformities and organ enlargement.

Purpose of the Study:

  • To describe the aetiology and primary clinical features of thalassaemia.
  • To outline the pathophysiological consequences of haemolysis in thalassaemia.
  • To detail the characteristic radiographic findings, particularly in bone structure.

Main Methods:

  • Review of the pathophysiology of thalassaemia.
  • Analysis of clinical manifestations and their link to haemolysis.
  • Correlation of erythropoietic stimulation with morphological bone changes.

Main Results:

  • Defective haemoglobin synthesis leads to haemolytic anaemia.
  • Stimulated erythropoiesis causes significant morphological changes in bone, including facial bones.
  • Radiographic evidence shows reduced cortical thickness and trabecular bone density.

Conclusions:

  • Thalassaemia's core issue is defective haemoglobin synthesis, causing anaemia and subsequent bone pathology.
  • Radiographic findings highlight skeletal involvement, including the facial bones.
  • Maxillofacial and dental interventions are generally not primary treatment concerns for thalassaemia itself.