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Updated: Jan 13, 2026

Quality-Controlled Sputum Analysis by Flow Cytometry

Quality-Controlled Sputum Analysis by Flow Cytometry

Published on: August 9, 2021

Digital Cytopathology Quality Guidelines.

Eric J Fish¹, Natalie Hoepp², Jennifer R Matlow³

¹EJF Veterinary Consulting, LLC, Tampa, Florida, USA.

Veterinary Clinical Pathology

|January 6, 2026

Summary

This summary is machine-generated.

New guidelines address digital cytopathology in veterinary medicine. These standards aim to improve diagnostic accuracy and workflow efficiency for veterinary pathologists and clinics using this technology.

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Area of Science:

Veterinary Pathology
Medical Technology
Laboratory Science

Background:

Digital cytopathology adoption is growing in veterinary medicine.
Lack of standardized quality guidance presents challenges in sample preparation, staining, and image analysis.
Emerging issues include scanner capabilities, software design, operator training, and optical resolution limits.

Purpose of the Study:

To provide comprehensive guidelines for digital cytopathology implementation in veterinary medicine.
To address preanalytical, analytical, and postanalytical phases of digital cytologic evaluation.
To enhance diagnostic accuracy, workflow efficiency, and clinical decision-making.

Main Methods:

Development of guidelines by the ASVCP Quality Assurance and Laboratory Standards Committee.
Focus on key recommendations for sample preparation, scanner/software validation, and operator training.
Establishment of procedures for image quality assessment and management of suboptimal scans.

Main Results:

Guidelines cover the entire digital cytologic evaluation process.
Recommendations emphasize standardized training and quality assessment.
Procedures are outlined for managing digital image quality and determining the need for glass slide review.

Conclusions:

The guidelines serve as a minimum standard for digital cytopathology in veterinary medicine.
These recommendations aim to ensure safe and effective implementation of the technology.
Guidelines will be revisited within five years due to rapid technological advancements and evolving evidence.