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Optimization of Breast Biopsy and Mastectomy Sample Collection Procedures for Biobanking, Personalized Medicine, and Research Applications
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RISE UP for breast cancer 2024: conference highlights & takeaways.

Taylor Glatt1, Katherine Leggat-Barr1, Nandini Seth2

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The Revolutionizing Investigations to StEp Up Prevention (RISE UP) conference explored novel breast cancer prevention strategies focusing on hormonal management throughout a woman's life. Key discussions included risk prediction, novel agents, and health equity to advance women's cancer care.

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Area of Science:

  • Oncology
  • Endocrinology
  • Public Health

Background:

  • Breast cancer prevention requires innovative approaches beyond current paradigms.
  • Hormonal management across the female life course is critical for risk reduction.
  • Integrating diverse expertise is essential for advancing prevention strategies.

Purpose of the Study:

  • To radically rethink breast cancer prevention and risk reduction through hormonal management.
  • To leverage existing knowledge in biology, detection, and treatment for sustainable prevention.
  • To explore the role of the hormonal environment and benign conditions in breast cancer risk.

Main Methods:

  • A global conference (RISE UP) convened diverse specialists and stakeholders.
  • Presentations focused on current knowledge and future directions in breast cancer prevention.
  • Discussions included risk prediction, risk-reducing agents, and biomarker-driven trials.

Main Results:

  • Explored managing the hormonal environment across life stages for risk minimization.
  • Considered biomarker-driven trials for prevention agents, repurposed drugs, and lifestyle interventions.
  • Emphasized health equity, reproductive health access, and reducing care disparities.

Conclusions:

  • RISE UP fostered cross-cutting discussions on women's health and breast cancer prevention.
  • Insights aim to be paradigm-shifting for future breast cancer prevention and women's health.
  • Innovative approaches to prevention integrated into hormonal and women's health interventions were highlighted.