Related Experiment Video
Updated: Jan 13, 2026

Network Pharmacology Prediction and Metabolomics Validation of the Mechanism of Fructus Phyllanthi against Hyperlipidemia
Published on: April 7, 2023
Monoterpenes from an aqueous extract of Paeonia lactiflora roots and their lipid-lowering effect
Jiawei Song1,2,3, Xinyi Du1,3, Shiqin Gong3
1Institute of life sciences, Zunyi Medical University, Zunyi, China.
Abstract:
A new monoterpene, 2',6'-di-O-galloylalbiflorin (1), along with four known analogues (2-5), was isolated from an aqueous extract of Paeonia lactiflora roots. The structural elucidation of these compounds was achieved through the application of key spectroscopic approaches, specifically HR-ESIMS and 1D/2D NMR. Their inhibitory effects on intestinal lipid accumulation were evaluated at 10 μM using Caenorhabditis elegans as an in vivo screening model. Among the tested compounds, 3 and 5 displayed the most significant activity in attenuating lipid deposition.
More Related Videos
09:15Differential Effects of Lipid-lowering Drugs in Modulating Morphology of Cholesterol Particles
Published on: November 10, 2017
14:39Semi-Targeted Ultra-High-Performance Chromatography Coupled to Mass Spectrometry Analysis of Phenolic Metabolites in Plasma of Elderly Adults
Published on: April 22, 2022
Related Concept Videos
Atherosclerosis III: Management
Lipid-Lowering Drugs: Statins and Miscellaneous Agents
Treatment for Pulmonary Arterial Hypertension: Endothelin Receptor Antagonists
ETs are synthesized through a complex sequence of enzymatic steps, primarily involving an enzyme referred to as endothelin-converting enzyme...
Cholesterol: Significance and Regulation
Considering cholesterol and...