[A targeted approach to cardiovascular risk in women: towards improved screening and prevention]

Manon Jouffroy1, Geneviève Plu-Bureau2, Claire Mounier-Vehier1

  • 1Univ. Lille, CHU Lille, Institut Cœur-Poumon, service de médecine vasculaire et hypertension artérielle, CHRU Lille, France.

Medecine Sciences : M/S
|January 6, 2026
PubMed

Insights

Cardiovascular risk in women involves unique factors like hormonal status and obstetric history, not covered by standard scores. Personalized prevention and better risk assessment are crucial for women's heart health.

Area of Science:

  • Cardiology
  • Women's Health
  • Public Health

Background:

  • Cardiovascular disease (CVD) risk factors in women differ significantly from men.
  • Standard CVD risk scores often fail to incorporate women-specific influences.
  • Hormonal status, obstetric history, and certain chronic conditions impact female cardiovascular risk.

Purpose of the Study:

  • To review and highlight women-specific factors influencing cardiovascular risk.
  • To emphasize the inadequacy of current risk assessment tools for women.
  • To advocate for tailored prevention strategies and improved health information for women.

Main Methods:

  • Literature review of studies focusing on sex-specific cardiovascular risk factors.
  • Analysis of how hormonal status, obstetric complications, and chronic inflammatory diseases affect arterial and venous risk.
  • Evaluation of existing cardiovascular risk stratification tools for their applicability to women.

Main Results:

  • Identified unique cardiovascular risk factors in women, including hormonal fluctuations, pregnancy complications (e.g., preeclampsia), endometriosis, and migraines.
  • Demonstrated that these factors influence both arterial and venous thromboembolic events.
  • Confirmed that standard cardiovascular risk calculators do not adequately address these sex-specific risks.

Conclusions:

  • Women's cardiovascular risk assessment requires integration of specific factors beyond traditional risk models.
  • Personalized prevention strategies and improved lifelong health education are essential for mitigating cardiovascular risk in women.
  • Development of novel risk stratification tools tailored to female physiology is urgently needed.

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