Related Experiment Video
Updated: Jan 13, 2026

Exploring the Neural Correlates of Cognitive Reappraisal in Obsessive-Compulsive Disorder Using Task-based Functional Magnetic Resonance Imaging
Published on: March 14, 2025
Imagery Rescripting and Behavioural Experiments for Mental Contamination in Obsessive-Compulsive Disorder: A Case
Elena Micheli1, Gabriele Melli1
1Institute for Behavioral and Cognitive Psychology and Psychotherapy, IPSICO, Florence, Italy.
Abstract:
This case study presents the treatment of a young adult with severe mental contamination (MC), a subtype of obsessive-compulsive disorder (OCD) characterized by internal feelings of dirtiness triggered by trauma-related emotions rather than physical contaminants. The patient, Federico, exhibited intense shame and disgust linked to a bullying episode, leading to compulsive rituals and functional impairments. Treatment integrated emotion regulation training, Imagery Rescripting (ImRs), and behavioral experiments, targeting dysfunctional beliefs about emotions. ImRs allowed reprocessing of the traumatic memory and reshaping of self-related meanings of impurity and unworthiness. Behavioral experiments tested and modified catastrophic appraisals of emotional experiences, fostering tolerance of distress without compulsive neutralization. By the end of treatment, Federico's Y-BOCS-II score fell from 42 to 15 (-64%) and his VOCI-MC score from 50 to 9 (-82%), with stability at 3-month follow-up. Follow-up confirmed the stability of gains and increased emotional autonomy. This case supports the utility of combining trauma-focused cognitive techniques and behavioral experiments in MC, particularly when compulsions are maintained by unprocessed emotional memories rather than concrete contamination threats. It highlights the need for individualized interventions in which ImRs may serve as a central component in treating MC symptoms.
Insights
This case study shows how combining emotion regulation, Imagery Rescripting (ImRs), and behavioral experiments effectively treated severe mental contamination (MC), a type of obsessive-compulsive disorder (OCD). Significant symptom reduction was achieved, improving the patient's emotional autonomy.
Area of Science:
- Psychiatry
- Clinical Psychology
- Trauma Studies
Background:
- Mental Contamination (MC) is an obsessive-compulsive disorder (OCD) subtype involving internal feelings of dirtiness triggered by emotions, not physical contaminants.
- Severe MC can lead to significant functional impairments and distress, often linked to trauma-related emotions like shame and disgust.
More Related Videos
Related Concept Videos
Obsessive-Compulsive Disorder
Operant Conditioning Intervention
In operant conditioning, behaviors that are...
Behavior Therapy
Exposure therapy is a cornerstone of behavioral treatment for anxiety disorders. It involves systematic exposure to feared stimuli, either in real...
Positive Symptoms of Schizophrenia: Hallucinations and Delusions
Thought Disorders
Disorganized and unusual thought processes mark thought disorders in schizophrenia. One key feature is disorganized speech, where an individual's conversation includes...
Modeling in Therapy
Participant Modeling
Participant modeling involves therapists demonstrating calm and effective behaviors in...
Introduction to Psychological Disorders
Deviant Behavior
Deviance in behavior refers to actions or thought patterns that significantly diverge from societal norms or...

