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Related Concept Videos

Peripheral Artery Disease III: Interprofessional Care01:27

Peripheral Artery Disease III: Interprofessional Care

236
Peripheral Artery Disease (PAD) is characterized by narrowed arteries that diminish blood flow to the extremities. Effective management of PAD requires an interprofessional approach involving various healthcare professionals. The critical aspects of interprofessional care for PAD patients focus on risk factor modification, drug therapy, exercise therapy, nutrition therapy, critical limb ischemia care, and interventional radiology and surgical procedures.The primary treatment goal for PAD...
236
Peripheral Artery Disease V: Postoperative Nursing Management01:23

Peripheral Artery Disease V: Postoperative Nursing Management

369
During the postoperative period, it is crucial to focus on maintaining circulation, identifying and managing potential complications, and planning for discharge.Nursing AssessmentVital signs monitoring: Regularly monitor vital signs, including blood pressure, heart rate, respiratory rate, and temperature, to detect early signs of complications such as bleeding and infection.Circulation assessment: Monitor pulses, perform Doppler assessments, and check capillary refill, color, temperature, and...
369
Peripheral Artery Disease I: Introduction01:30

Peripheral Artery Disease I: Introduction

302
Peripheral artery disease (PAD) predominantly results from atherosclerosis, which involves the accumulation of fatty deposits, or plaques, within the walls of arteries. This causes them to narrow and harden, significantly reducing blood flow. PAD predominantly affects the legs, particularly the arteries supplying the thighs and calves. In rare cases, it may involve other arteries, including those in the arms.Etiology of PAD:The principal cause of PAD is atherosclerosis, which results from fatty...
302
Peripheral Artery Disease IV: Nursing Management01:26

Peripheral Artery Disease IV: Nursing Management

342
 The nursing management of a patient with peripheral artery disease (PAD) begins with a thorough assessment of the patient’s health history and clinical manifestations.AssessmentHealth History: Evaluate the patient’s history of hypertension, hyperlipidemia, family history of cardiovascular issues, and lifestyle factors such as dietary patterns, smoking, and physical activity.Physical Examination:Assess the affected extremity for decreased or absent peripheral pulses,...
342
Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation01:21

Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation

346
Clinical manifestationsPeripheral Arterial Disease (PAD) manifests through a range of symptoms, from the characteristic intermittent claudication to atypical presentations and severe complications in advanced stages. Intermittent claudication, a hallmark symptom of PAD, presents as exercise-induced muscle pain that typically resolves within minutes of rest. This pain is reproducible and stems from inadequate blood flow, leading to the accumulation of lactic acid produced during anaerobic...
346
Hemodialysis I: Introduction01:25

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Hemodialysis (HD) is a medical treatment that artificially removes waste products, excess fluids, and toxins from the blood when the kidneys are no longer able to perform these functions effectively. In this process, blood is filtered through a semipermeable membrane, allowing for the selective removal of waste while preserving necessary components like blood cells and proteins. Hemodialysis is typically performed in patients with end-stage renal disease (ESRD) or severe kidney...
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Updated: Jan 13, 2026

Reduction of Radiation Exposure during Endovascular Treatment of Peripheral Arterial Disease Combining Fiber Optic RealShape Technology and Intravascular Ultrasound
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Atherectomy for peripheral arterial disease.

Siddhant Pherwani1, Ahmed Gendia2, Shampa Sen3

  • 1Renal Transplant Surgery, Hammersmith Hospital, Imperial College Healthcare NHS Trust, London, UK.

The Cochrane Database of Systematic Reviews
|January 6, 2026
PubMed
Summary
This summary is machine-generated.

Current evidence on atherectomy for peripheral arterial disease (PAD) is uncertain. This review found no significant differences in outcomes compared to balloon angioplasty, but more research is needed.

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Area of Science:

  • Vascular Surgery
  • Interventional Cardiology
  • Evidence-Based Medicine

Background:

  • Peripheral arterial disease (PAD) is a common condition caused by narrowed lower limb arteries.
  • Atherectomy is an endovascular technique to remove arterial plaque, but its effectiveness compared to conventional treatments remains unclear.
  • The use of atherectomy for PAD is increasing, necessitating a clear understanding of its benefits and harms.

Purpose of the Study:

  • To evaluate the benefits and harms of atherectomy versus other treatments for peripheral arterial disease.
  • This review is an update of a Cochrane review, focusing on randomized controlled trials.

Main Methods:

  • Searched multiple databases (CENTRAL, MEDLINE, Embase, CINAHL, AMED) and clinical trial registries.
  • Included randomized controlled trials comparing atherectomy with other established treatments in symptomatic PAD patients.
  • Assessed risk of bias using Cochrane RoB 1 tool and synthesized results using meta-analysis, with outcomes including primary patency, mortality, cardiovascular events, revascularization, and complications.

Main Results:

  • Eleven studies with 814 participants were included, comparing atherectomy to balloon angioplasty (BA) or BA with stenting.
  • No significant differences were found in primary patency, mortality, cardiovascular events, target vessel revascularization, or complication rates between atherectomy and BA.
  • Evidence for atherectomy versus stenting was limited, with no clear differences in outcomes, but the certainty of evidence for all comparisons was very low due to high risk of bias and imprecision.

Conclusions:

  • The current evidence on atherectomy for PAD remains highly uncertain.
  • There is no clear evidence of benefit or harm compared to balloon angioplasty or stenting.
  • Larger, high-quality studies are required to determine the efficacy and safety of atherectomy in PAD management.