Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Neuroplasticity01:01

Neuroplasticity

1.6K
Neuroplasticity reflects the brain's remarkable capacity to adapt and evolve, responding dynamically to learning, experiences, or injury by reorganizing its neural circuitry. This reorganization involves creating new neural connections and refining old ones through a series of biological processes that contribute to the brain's lifelong development and adaptability.
1.6K
Stress Prevention and Stress Management Techniques I01:26

Stress Prevention and Stress Management Techniques I

272
Stress prevention and management are crucial for maintaining well-being and building resilience. Techniques to manage stress include cultivating qualities like conscientiousness, a sense of personal control, and self-efficacy. Each of these traits significantly reduces stress and promotes healthier lifestyle choices and outcomes.
Conscientiousness
Conscientious individuals tend to be organized, responsible, and disciplined. They prioritize completing tasks and following structured routines,...
272
Natural Selection and Adaptation01:15

Natural Selection and Adaptation

1.2K
Natural selection, a fundamental concept in evolutionary biology, is the mechanism by which evolution is driven, favoring organisms that are best adapted to their environments. This process enhances their chances of survival and reproduction. Adaptation, a key outcome of this process, involves genetic modifications that optimize an organism's functionality under specific environmental challenges, such as extreme cold or thinner air at high altitudes.
Beyond physical adaptations,...
1.2K
Unrealistic Optimism Bias01:30

Unrealistic Optimism Bias

201
Unrealistic optimism bias is the tendency to overestimate the likelihood of positive outcomes. This cognitive bias makes individuals believe they are less likely to experience failures, setbacks, or risks and more likely to succeed than others. For example, people may assume they are less prone to health issues, accidents, or financial struggles than their peers, even when they share similar risk factors.One key component of this bias is the above-average effect, where individuals perceive...
201
Stress Prevention and Stress Management Techniques II01:23

Stress Prevention and Stress Management Techniques II

487
Personality types, particularly Type A and Type B, significantly influence how individuals respond to stress. These personality distinctions are marked by varying levels of ambition, competitiveness, and coping styles, all of which shape an individual's resilience to stressors.
Type A Personality: Driven and Easily Stressed
Individuals with Type A personalities are often highly competitive and ambitious and operate with a strong sense of urgency. Commonly labeled as...
487
Psychological Responses to Stress01:20

Psychological Responses to Stress

472
Psychological responses to stress encompass the various cognitive and emotional reactions individuals experience when faced with challenging or threatening situations, such as a job loss. Prolonged exposure to stressors can disturb emotional balance, increasing negative emotions (e.g., anxiety and sadness) and diminishing positive emotions (e.g., joy and satisfaction). These persistent emotional shifts are associated with an increased risk of both physical illness and mental health issues, such...
472

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A hypothalamic circuit for anticipating future changes in energy balance.

Neuron·2026
Same author

A spatial and projection-based transcriptomic atlas of paraventricular hypothalamic cell types.

Cell reports·2026
Same author

A hypothalamic circuit for anticipating future changes in energy balance.

bioRxiv : the preprint server for biology·2025
Same author

Preoptic EP3R neurons constitute a two-way switch for fever and torpor.

Nature·2025
Same author

Acute and circadian feedforward regulation of agouti-related peptide hunger neurons.

Cell metabolism·2024
Same author

Repeated stress triggers seeking of a starvation-like state in anxiety-prone female mice.

Neuron·2024

Related Experiment Video

Updated: Jan 13, 2026

Author Spotlight: Unveiling Mechanisms of Stress Resilience - Significant Findings, Advancements, and Future Research
05:03

Author Spotlight: Unveiling Mechanisms of Stress Resilience - Significant Findings, Advancements, and Future Research

Published on: December 15, 2023

4.9K

Neuroscience: What doesn't kill you makes you stronger.

Hakan Kucukdereli1, Amelia M Douglass1

  • 1Institute of Science and Technology Austria (ISTA), Am Campus 1, 3400 Klosterneuburg, Austria.

Current Biology : CB
|January 6, 2026
PubMed
Summary

The psychedelic drug psilocybin triggers immediate stress hormone release. This occurs despite psilocybin

Area of Science:

  • Neuroscience
  • Pharmacology
  • Endocrinology

Background:

  • Mild stress can be beneficial.
  • Psilocybin is a psychedelic compound known for long-term anxiolytic effects.

Purpose of the Study:

  • To investigate the acute effects of psilocybin on the stress response system.
  • To elucidate the mechanism behind psilocybin's acute stress hormone release.

Main Methods:

  • Administration of psilocybin to study participants.
  • Measurement of key stress hormones (e.g., cortisol, ACTH).
  • Analysis of the temporal relationship between psilocybin intake and hormone levels.

Main Results:

  • Psilocybin administration led to a rapid and significant increase in circulating stress hormones.

More Related Videos

Author Spotlight: Understanding Adolescent Social Adversity Effects on Neurodevelopment in Mice
07:15

Author Spotlight: Understanding Adolescent Social Adversity Effects on Neurodevelopment in Mice

Published on: March 15, 2024

2.4K
A Modified Trier Social Stress Test for Vulnerable Mexican American Adolescents
06:15

A Modified Trier Social Stress Test for Vulnerable Mexican American Adolescents

Published on: July 10, 2017

13.4K

Related Experiment Videos

Last Updated: Jan 13, 2026

Author Spotlight: Unveiling Mechanisms of Stress Resilience - Significant Findings, Advancements, and Future Research
05:03

Author Spotlight: Unveiling Mechanisms of Stress Resilience - Significant Findings, Advancements, and Future Research

Published on: December 15, 2023

4.9K
Author Spotlight: Understanding Adolescent Social Adversity Effects on Neurodevelopment in Mice
07:15

Author Spotlight: Understanding Adolescent Social Adversity Effects on Neurodevelopment in Mice

Published on: March 15, 2024

2.4K
A Modified Trier Social Stress Test for Vulnerable Mexican American Adolescents
06:15

A Modified Trier Social Stress Test for Vulnerable Mexican American Adolescents

Published on: July 10, 2017

13.4K
  • The acute hormonal response was observed shortly after administration.
  • This acute effect contrasts with psilocybin's established long-term anxiety-reducing properties.

    • Conclusions:

    • Psilocybin induces an acute stress response characterized by the release of stress hormones.
    • Understanding this mechanism is crucial for managing psilocybin's therapeutic potential and side effects.
    • Further research is needed to reconcile the acute stress response with long-term anxiolytic outcomes.