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Updated: Jan 13, 2026

The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis
Published on: July 11, 2013
Relationship between recurrent colorectal cancer and EGFR inhibitor-induced dermatological side effects: a focus on
Omer Esmez1, Merve Yıldız Esmez2, Gulnİhal Deniz3
1Ortopedia and travmatology, Elazığ Fethi Sekin City Hospital, Elâzığ, Turkey dresmezomer@gmail.com.
Abstract:
This case describes a woman in her mid-40s with recurrent colorectal cancer who developed severe dermatologic toxicity during panitumumab-based therapy. Three months after treatment initiation, she developed a diffuse acneiform eruption, pronounced xerosis and painful periungual inflammation with exuberant granulation tissue consistent with epidermal growth factor receptor (EGFR)-inhibitor-induced paronychia. Multidisciplinary, guideline-concordant supportive care (including prompt topical measures and short-course systemic therapy) achieved symptom control and allowed continuation of anticancer treatment. This report underscores the importance of early recognition and structured management of EGFR-inhibitor toxicities to prevent treatment disruption and preserve quality of life.
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