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Related Concept Videos

  • Physical Sciences
  • Condensed Matter Physics
  • Surface Properties Of Condensed Matter
  • Quantifying Ocular Surface Changes With Contact Lens Wear.
  • Physical Sciences
  • Condensed Matter Physics
  • Surface Properties Of Condensed Matter
  • Quantifying Ocular Surface Changes With Contact Lens Wear.

    • Related Experiment Video

    Development of an In Vitro Ocular Platform to Test Contact Lenses
    08:28

    Development of an In Vitro Ocular Platform to Test Contact Lenses

    Published on: April 6, 2016

    11.2K

    Quantifying ocular surface changes with contact lens wear.

    Lucia Carichino1, Kara L Maki1, David S Ross1,2

    • 1School of Mathematics and Statistics, Rochester Institute of Technology, 85 Lomb Memorial Drive, Rochester, NY 14623, USA.

    Mathematical Biosciences and Engineering : MBE
    |January 6, 2026

    View abstract on PubMed

    Summary
    This summary is machine-generated.

    This study introduces a novel mathematical model to simulate contact lens and eye interactions, revealing how lens properties influence ocular stress and deformation. The findings offer insights into contact lens discomfort and ocular surface health.

    Keywords:
    contact lens comfortfinite element simulationsnon-linear couplingocular biomechanicssuction pressure

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    Related Experiment Videos

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    Area of Science:

    • Biomechanical Engineering
    • Ophthalmology
    • Computational Modeling

    Background:

    • Millions use contact lenses, with many discontinuing use due to discomfort.
    • Mechanical interactions between contact lenses and the ocular surface are poorly understood and difficult to quantify clinically.
    • Existing research on these interactions is limited.

    Purpose of the Study:

    • To develop the first mathematical model simulating contact lens-ocular surface mechanical interactions.
    • To predict emergent properties like lens configuration, suction pressure, and ocular deformation.
    • To analyze the influence of various parameters on these interactions.

    Main Methods:

    • Developed a non-linear mathematical model coupling contact lens mechanics with ocular surface biomechanics.
    • Modeled suction pressure applied through the post-lens tear film.
    • Incorporated homogeneous/heterogeneous linear elastic eye models, varied ocular and lens shapes/thicknesses.

    Main Results:

    • Predicted higher ocular deformations and stresses at the central and limbal/scleral regions.
    • Demonstrated that heterogeneous eye material properties amplify ocular stress and deformation.
    • Showed non-linear increases in ocular displacement and stress with increased contact lens stiffness.
    • Found steeper lenses reduce central ocular displacement but increase peripheral displacement.

    Conclusions:

    • The model provides a quantitative framework for understanding contact lens biomechanics and ocular surface response.
    • Findings highlight the significant impact of contact lens design and material properties on ocular health.
    • The model's predictions align with existing experimental data and theoretical models.