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Crossover Experiments

Crossover Experiments

Crossover experiments, also called the repeated-measurements design, is a study design in which all experimental units are exposed to all treatments in different periods. Crossover experiments are generally used in psychology, the pharmaceutical industry, agriculture, and medicine.
Crossover designs are performed even with smaller sample sizes since the samples can act as their controls. These are better than simple randomized trials since patients are exposed to all the treatments.

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Related Experiment Video

Updated: Jan 13, 2026

Automated, Quantitative Cognitive/Behavioral Screening of Mice: For Genetics, Pharmacology, Animal Cognition and Undergraduate Instruction

Automated, Quantitative Cognitive/Behavioral Screening of Mice: For Genetics, Pharmacology, Animal Cognition and Undergraduate Instruction

Published on: February 26, 2014

Concerns about attributing weight change to processing in a crossover feeding trial

Zixuan Wang¹, Can Peng^2,3

¹ZHT Lab Co., Ltd, Beijing, China. zixuanwang@zhtlab.com.

Nature Medicine

|January 6, 2026

Summary

No abstract available in PubMed .

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