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Updated: Jan 13, 2026

Generation of Prostate Cancer Cell Models of Resistance to the Anti-mitotic Agent Docetaxel
Published on: September 8, 2017
EXPRESSION OF CONCERN: Functional p53 Determines Docetaxel Sensitivity in Prostate Cancer Cells
Expression Of Concern:
C. Liu, Y. Zhu, W. Lou, N. Nadiminty, X. Chen, Q. Zhou, X. B. Shi, R. W. deVere White, and A. C. Gao, "Functional p53 Determines Docetaxel Sensitivity in Prostate Cancer Cells," The Prostate 73, no. 4 (2013): 418-427, https://doi.org/10.1002/pros.22583. This Expression of Concern is for the above article, published online on 19 September 2012 in Wiley Online Library (wileyonlinelibrary.com), and has been issued by agreement between the journal Editor-in-Chief, Dr. Samuel Denmeade; and Wiley Periodicals LLC. A third party reported that the GAPDH band had been duplicated between Figures 4 A and 5B. This duplication was confirmed by the publisher. The authors responded to an inquiry by the publisher and stated that the GAPDH band in Figure 5B was inadvertently misplaced and duplicated from Figure 4 A. The authors also supplied images and data related to Figures 4 and 5. An evaluation of this data could not confirm that the corrected image for the GAPDH band in Figure 5B corresponded to data collected from the original experiments. This Expression of Concern has been agreed to because the journal is not able to validate some experimental data for Figures 4 and 5. The authors disagree with the Expression of Concern.
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