Efforts to Enhance Recruitment and Engagement of Caregivers from Medically Underserved Communities in a Randomized Controlled Trial of a Vaccine Promotion App
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View abstract on PubMed
Summary
This summary is machine-generated.This study successfully recruited diverse children for a COVID-19 vaccine trial, addressing disparities in vaccine adoption among underserved populations. The findings highlight effective strategies for engaging underrepresented groups in pediatric research.
Area Of Science
- Pediatric Health
- Vaccine Research
- Health Equity
Background
- Over 15 million US children contracted COVID-19, with nearly 2,000 deaths.
- COVID-19 vaccine approval for children reduced disease severity and mortality.
- Significant racial, ethnic, and rural-urban disparities exist in pediatric COVID-19 vaccine uptake.
Purpose Of The Study
- To examine recruitment and engagement strategies for a diverse cohort in a pediatric vaccine communication randomized trial.
- To compare the demographic characteristics of the enrolled cohort with the broader US population.
- To assess the effectiveness of targeted recruitment methods in reaching medically underserved populations.
Main Methods
- A randomized trial was conducted across 15 states, focusing on clinics serving medically underserved populations.
- Recruitment utilized traditional (clinic schedule review) and retrospective (EHR/billing data) methods.
- Demographic data of enrolled participants were compared to national statistics from the CDC's Household Pulse Survey.
Main Results
- 2999 parents/caregivers were screened, with 725 (24.1%) randomized.
- The enrolled cohort showed higher representation of Hispanic (17.3% vs 9.8%) and Black (39.6% vs 13.0%) individuals compared to state demographics.
- 34.3% of participants resided in rural areas, and high survey completion rates (70.6% baseline, 82.4% final) were achieved.
Conclusions
- The Institutional Development Award States Pediatric Clinical Trials Network successfully recruited and engaged diverse and underrepresented populations.
- Targeted recruitment strategies are effective in enrolling medically underserved children in vaccine research.
- These findings support efforts to reduce disparities in pediatric vaccine research participation.
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