A Novel Method for Generating Spatially Resolved Synthetic Populations for Health Impact Assessments in Vulnerable
Flannery Black-Ingersoll1, Chad W Milando1, Zachary T Popp1
1Department of Environmental Health Boston University School of Public Health Boston MA USA.
Geohealth
|January 7, 2026
Summary
A new algorithm creates address-level synthetic populations, improving environmental justice and health impact analyses by accurately matching individuals to environmental exposures. This method enhances accuracy over random allocation.
Area of Science:
- Environmental Health
- Spatial Epidemiology
- Computational Social Science
Background:
- Mismatched spatial resolution between environmental exposure and sociodemographic data limits public health analyses.
- Privacy concerns restrict the availability of fine-grained population data.
Purpose of the Study:
- To develop and validate a novel algorithm for constructing address-level synthetic populations.
- To assess the impact of this synthetic population method on environmental justice (EJ) and health impact assessments (HIAs).
Main Methods:
- Developed a combinatorial optimization algorithm to create a synthetic population at the census tract level.
- Downscaled the synthetic population to the address level by matching building attributes.
- Compared address-level exposure assignment using the synthetic population versus random allocation for EJ and HIA.
Main Results:
- Significant misclassification of individual households occurred when using random address allocation compared to the matched synthetic population (21% error).
- Aggregate differences in exposure and income were modest (3.3% vs. 3.4% low-income/high-exposure households).
- Health impact assessments showed stronger differences with the synthetic population, especially with interactive effects.
Conclusions:
- Address-level synthetic populations enhance the precision and nuance of environmental justice and health impact analyses.
- The novel matching algorithm offers a privacy-preserving solution for integrating disparate data sources.
- This methodology is adaptable for broader applications in public health research across different regions and vulnerability dimensions.
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