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Updated: Jan 13, 2026
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Conducting Respiratory Oscillometry in an Outpatient Setting
Published on: April 8, 2022
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Reference equations for oscillometry in adults: data from the Austrian LEAD study
Christoph Valach1,2,3, Christoph Gross1,2, Chiara Veneroni4
1Ludwig Boltzmann Institute for Lung Health, Vienna, Austria.
ERJ Open Research
|January 7, 2026
Summary
This study establishes new reference values for respiratory impedance measurements in adults using oscillometry. These findings provide a narrower, more accurate range for diagnosing respiratory conditions.
Area of Science:
- Respiratory physiology
- Pulmonary diagnostics
- Medical device calibration
Background:
- Establishing reference values for respiratory impedance (Z) measured by oscillometry is crucial for clinical application.
- Oscillometry is a key technique for assessing respiratory mechanics.
Purpose of the Study:
- To develop reference values for within-breath and total oscillometry measurements in adults aged 18-90 years.
- To create sex-specific reference equations for various oscillometry parameters.
Main Methods:
- Analysis of data from 887 healthy, asymptomatic, never-smoking adults from the Austrian LEAD study cohort.
- Utilized the Resmon Pro FULL® device with multiple frequency mode (5-11-19 Hz).
- Developed sex-specific reference equations using the lambda, mu, sigma method, incorporating height, age, and BMI.
Main Results:
- Generated sex-specific reference equations for 30 total and within-breath oscillometry parameters.
- Height was identified as the strongest predictor in the models.
- The derived predicted values demonstrated a narrower range of normality compared to existing equations.
Conclusions:
- The study provides highly accurate adult reference equations based on a large, diverse age group.
- These reference equations will aid further research into the role of oscillometry in respiratory diagnostics.
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