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Factitious Cheilitis: Report of Two Cases.

Daniel Mauricio Cuestas Rodriguez1, Tatiana Carolina Reyes Vivas2, Luis Daniel Pérez Cáceres3

  • 1Universidad el Bosque, Simón Bolívar Hospital Bogotá D.C. Colombia.

Clinical Case Reports
|January 7, 2026
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Summary

Factitious cheilitis (FC), a self-inflicted lip condition, is often misdiagnosed. Recognizing this rare psychodermatologic disorder is crucial for appropriate management and avoiding unnecessary treatments.

Keywords:
differential diagnosisfactitious cheilitislip lesionspsychiatric comorbiditypsychodermatologyself‐inflicted dermatoses

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Area of Science:

  • Dermatology
  • Psychiatry
  • Psychodermatology

Background:

  • Factitious cheilitis (FC) is a rare psychodermatologic condition.
  • It is often underdiagnosed and misdiagnosed as infectious or neoplastic lip conditions.
  • Self-inflicted trauma to the lips characterizes FC.

Purpose of the Study:

  • To highlight the diagnostic challenges associated with Factitious Cheilitis.
  • To emphasize the importance of identifying self-inflicted dermatoses in clinical practice.
  • To underscore the need for a multidisciplinary approach in managing FC.

Main Methods:

  • Case report of two young adult females with verrucous lip lesions.
  • Initial differential diagnoses included squamous cell carcinoma and pustular cheilitis.
  • Diagnosis confirmed by clinical history and behavioral patterns indicating self-inflicted trauma.

Main Results:

  • Histopathologic findings were nonspecific.
  • Both patients were diagnosed with Factitious Cheilitis.
  • Management involved topical treatment and psychological support referral.

Conclusions:

  • FC presents diagnostic challenges and can be mistaken for other lip conditions.
  • Recognizing self-inflicted dermatoses is vital to prevent unnecessary procedures.
  • Consider FC in chronic cheilitis with atypical lesions, especially with psychiatric comorbidities.