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Localized Immune-Complex Small-Vessel Vasculitis Presenting as Unilateral Myositis After Hepatitis A
Mariam Zeidan1, Rita Abou Zeid2, Hajar Alhusani2
1Faculty of Medicine, American University of Beirut, Beirut, LBN.
This case study details the first instance of unilateral immune-complex small-vessel vasculitis (ICSVV) affecting leg muscles, triggered by Hepatitis A virus (HAV) infection. Prompt immunosuppressive treatment led to remission, highlighting early diagnosis importance.
Area of Science:
- Rheumatology and Immunology
- Infectious Diseases
- Vascular Medicine
Background:
- Immune-complex small-vessel vasculitis (ICSVV) involves immune complex deposition in small blood vessels, leading to inflammation and necrosis.
- Hepatitis A virus (HAV) is an uncommon trigger for vasculitis, unlike hepatitis B and C.
- Vasculitic myositis, inflammation of muscles due to vasculitis, is typically bilateral and symmetric, with few reports of unilateral or muscle-limited disease.
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