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Updated: Aug 7, 2026

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Intravascular Adenomyosis in a Cynomolgus Macaque (Macaca Fascicularis)
Hannah M Ruetten1,2, Abolfazl S Abdolmaleki1, Anthony Atala1
1Wake Forest Institute for Regenerative Medicine, Wake Forest Baptist Medical Center, North Carolina, USA.
Abstract:
Intravascular adenomyosis was discovered in a cynomolgus macaque, a previously unreported presentation of adenomyosis in non-human primates that points to vascular involvement in adenomyosis etiology. Uterus gross exam was unremarkable, but histologic examination revealed multifocal endometrial tissue intimately associated with large thin-walled myometrial vessels and surrounded by CD31 immunopositive endothelium.
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