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Related Concept Videos

Parkinson's Disease: Treatment01:24

Parkinson's Disease: Treatment

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Neurodegenerative disorders, such as Parkinson's Disease (PD), involve the gradual and irreversible destruction of neurons in particular brain areas. These disorders exhibit standard features like proteinopathies, selective vulnerability of some neurons, and an interaction of intrinsic properties, genetics, and environmental influences in neural injury.
Parkinson's Disease is primarily a result of the loss of dopaminergic neurons in the substantia nigra pars compacta. The cornerstone of...
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Parkinson's Disease: Overview01:15

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Neurodegenerative disorders are progressive diseases that cause irreversible damage and loss to neurons in specific brain areas. Examples of these disorders include Parkinson's disease, Alzheimer's disease, Multiple Sclerosis (MS), and Amyotrophic Lateral Sclerosis (ALS). These disorders share characteristics such as proteinopathies, selective neuronal vulnerability, and a complex interplay between genetic and environmental factors. The primary therapeutic goal for these conditions is...
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Controlling Parkinson's Disease With Adaptive Deep Brain Stimulation
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Patient-Reported Communication Decline Following Deep Brain Stimulation in Parkinson's Disease.

Stephanie M Simone1,2, Federico Rodriguez-Porcel3, Travis H Turner3

  • 1Department of Psychiatry, Medical University of South Carolina, Charleston, South Carolina, USA.

Movement Disorders Clinical Practice
|January 7, 2026
PubMed
Summary
This summary is machine-generated.

People with Parkinson's disease (PwP) report decreased communication effectiveness after subthalamic nucleus Deep Brain Stimulation (DBS). This subjective decline was not linked to cognitive changes, highlighting the importance of patient-reported outcomes.

Keywords:
CPIBParkinson's diseasecommunicationdeep brain stimulationspeech and language

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Area of Science:

  • Neuroscience
  • Speech-Language Pathology
  • Neurology

Background:

  • Communication deficits are common in Parkinson's disease (PD) patients undergoing Deep Brain Stimulation (DBS).
  • Patient perspectives on communication changes post-DBS are under-researched.
  • Subthalamic nucleus DBS is a common treatment for PD.

Purpose of the Study:

  • To investigate subjective changes in communicative efficacy in People with Parkinson's disease (PwP) after subthalamic nucleus DBS.
  • To assess patient-reported outcomes using the Communicative Participation Item Bank (CPIB).

Main Methods:

  • Thirty PwP undergoing subthalamic nucleus DBS were evaluated.
  • Paired t-tests were used to analyze changes in CPIB scores.
  • Correlations between CPIB changes and cognitive/language measures were examined.

Main Results:

  • A statistically significant decline in subjective communication efficacy (CPIB scores) was observed post-DBS.
  • CPIB decline did not correlate with objective language performance changes.
  • No association was found between CPIB decline and DBS laterality or pre-DBS cognitive status.

Conclusions:

  • Subjective communication decline is prevalent in PwP following STN-DBS.
  • Patient-reported communication efficacy post-DBS is not directly linked to objective language or cognitive function.
  • Integrating patient-reported outcomes like the CPIB is crucial for comprehensive DBS evaluations and understanding communication risks.