The burden of non-CLABSI hospital-onset bloodstream ınfections in pediatric wards outside the ıntensive care units
These videos have been matched automatically. Contact us if they are not relevant.
These videos have been matched automatically. Contact us if they are not relevant.
View abstract on PubMed
Summary
This summary is machine-generated.Hospital-onset bacteremia and candidemia (HOB/HOC) outside intensive care units significantly impact pediatric patients, prolonging hospital stays. Enhanced surveillance and prevention strategies are crucial for these non-central line-associated infections.
Area Of Science
- Pediatric Infectious Diseases
- Healthcare-Associated Infections
- Clinical Microbiology
Background
- Central line-associated bloodstream infections (CLABSIs) are well-studied, but non-CLABSI hospital-onset bacteremia and candidemia (HOB/HOC) in non-intensive care unit (ICU) pediatric patients are poorly understood.
- Limited epidemiologic and clinical data exist for pediatric HOB/HOC outside of ICUs.
Purpose Of The Study
- To characterize the epidemiology and clinical features of non-CLABSI HOB/HOC in pediatric patients admitted to general wards.
- To identify common pathogens and clinical sources associated with these infections.
- To assess the impact of non-CLABSI HOB/HOC on hospitalization duration.
Main Methods
- Retrospective analysis of pediatric patients (1 month-18 years) admitted to a tertiary hospital from January 2021 to January 2025.
- Inclusion criteria: first positive blood culture for a non-commensal organism on or after hospital day 4, without central venous catheters, peripherally inserted central catheters, or ICU stay.
- Collection of demographic, clinical, microbiological, and outcome data.
Main Results
- 29 episodes of non-CLABSI HOB/HOC were identified among 14,985 blood cultures.
- The most frequent pathogens included Escherichia coli, Staphylococcus aureus, Coagulase-negative staphylococci, Candida species, and Klebsiella pneumoniae.
- Common clinical sources were skin/soft tissue infections, peripheral intravenous catheter thrombophlebitis, urinary, and respiratory infections. Patients experienced a median of 11 extra hospitalization days.
Conclusions
- Non-CLABSI HOB/HOC represent a significant cause of morbidity in pediatric general wards.
- These infections are associated with diverse pathogens, including resistant strains, and lead to prolonged hospital stays.
- Infection prevention efforts should encompass peripheral devices and be supported by improved surveillance and definitions.
These videos have been matched automatically. Contact us if they are not relevant.
These videos have been matched automatically. Contact us if they are not relevant.
Related Concept Videos
Healthcare-associated infections (HAIs) occur in a healthcare facility while a person receives care for another ailment. This category also includes work-related infections among healthcare staff.
HAIs significantly increase the cost of health care. Extended stays in healthcare institutions, increased disability, increased costs of medications, including specialized antibiotics, and prolonged recovery times add to the patient's expenses and the healthcare institution and funding bodies.
Essential infection prevention measures are based on the knowledge of the infection chain, the modes of transmission in healthcare settings, and the use of the best practices in all healthcare settings. Compulsory public reporting of healthcare-associated infection rates is needed to allow individuals and the community to make informed choices regarding selecting a healthcare facility.
The best practices for preventing healthcare-associated infections include hand hygiene, patient risk...
In pediatric medicine, understanding the renal function and drug elimination nuances is crucial for administering safe and effective treatments. Newborns, in particular, display markedly slower renal functions than adults, profoundly affecting how drugs are cleared from their bodies. This slower drug clearance requires clinicians to extend the dosing intervals for many medications to prevent drug accumulation and toxicity while ensuring therapeutic efficacy.One key area where these adjustments...
Pneumonia is an acute respiratory infection that targets the lungs, specifically the alveoli. These tiny air sacs, essential for oxygen exchange, become engorged with pus and fluid, severely hindering breathing, decreasing oxygen absorption, and causing significant pain and discomfort during respiration.
Risk Factors
Various factors influence the likelihood of developing pneumonia. Age plays a crucial role, with infants, children under two, and individuals over 65 at increased risk due to their...
Introduction:For diagnosing acute pyelonephritis, a comprehensive patient history is collected to identify symptoms such as dysuria, frequent or urgent urination, flank pain, or costovertebral angle (CVA) tenderness that may suggest a kidney infection.Physical ExaminationDuring the physical examination, CVA tenderness is assessed. This involves gentle percussion over the costovertebral angle, where tenderness often indicates a kidney infection.Diagnostic TestsUrinalysis: Used to identify white...
Introduction:Endocarditis is the infection of the endocardium, the inner lining of the heart and its valves. When the heart muscle is involved, the condition is termed myocarditis, while an infection of the outer lining is called pericarditis. Infective endocarditis (IE) primarily affects the endocardium, where pathogens adhere to the valves or lining, forming vegetation that can lead to severe complications. Infective endocarditis occurs when microorganisms, usually bacteria from other body...