Systematic Review and Metanalysis on the Advanta V12/iCast Outcomes as Bridging Stent in Iliac Branch Devices
George Apostolidis1, Konstantinos Dakis2, José I Torrealba1
1German Aortic Centre, Department of Vascular Medicine, University Heart and Vascular Centre UKE Hamburg, Hamburg, Germany.
Summary
The Advanta V12/iCast bridging stent demonstrates high technical success (98%) and low complication rates for iliac branch device procedures. This meta-analysis suggests it is a reliable choice for preserving internal iliac artery perfusion.
Area of Science:
- Vascular Surgery
- Interventional Radiology
- Medical Device Technology
Background:
- Iliac branch devices (IBDs) are crucial for maintaining internal iliac artery (IIA) perfusion.
- Limited data exists on optimal bridging stent selection for IBD procedures.
Purpose of the Study:
- To evaluate the outcomes of the Advanta V12/iCast stent when used as a bridging stent in IBD procedures.
- To assess technical success, stenosis/occlusion, endoleak, and reintervention rates.
Main Methods:
- Systematic literature search of PubMed, Scopus, and Cochrane Library.
- Inclusion of 10 observational studies (2000-2025) with 467 bridged IIAs.
- Proportional meta-analysis of primary outcomes, with risk of bias and quality of evidence assessment (ROBINS-I, GRADE).
Main Results:
- High technical success rate of 98% for Advanta V12/iCast.
- Low 30-day rates: occlusion/stenosis (2%), endoleak Ic/IIIc (0.3%), reintervention (1%).
- Low follow-up rates: occlusion/stenosis (4%), endoleak Ic/IIIc (5%), reintervention (5%) over a mean of 23.4 months.
Conclusions:
- Advanta V12/iCast shows favorable outcomes, indicating reliability as a bridging stent in IBDs.
- Low rates of occlusion/stenosis, endoleak, and reintervention support its use.
- Low quality of evidence necessitates cautious interpretation of results.
