Unilateral Cleft Lip Repair: Reproducibility, Accessibility, and Durability

Usama S Hamdan1, Roland K Assaf1, Jana Zeineddine2

  • 1Global Smile Foundation, Norwood, MA.

PubMed
Summary

A refined technique for unilateral cleft lip (UCL) repair offers a simplified, reproducible method for consistent outcomes, addressing global access challenges in cleft care.

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Fixing Double-strand Breaks02:04

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Base Excision Repair01:54

Base Excision Repair

One of the common DNA damages is the chemical alteration of single bases by alkylation, oxidation, or deamination. The altered bases cause mispairing and strand breakage during replication. This type of damage causes minimal change to the DNA double helix structure and can be repaired by the base excision repair (BER) pathways. BER corrects damaged DNA sequences by removing the damaged base and restoring the original base sequence using the complementary strand as a template.
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