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Working Memory Training for Older Participants: A Control Group Training Regimen and Initial Intellectual Functioning Assessment
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Preserved muscle function as a protective factor against cognitive decline: Longitudinal results from the FINGER
Miguel German Borda1,2, Jenni Lehtisalo3,4, Kevin O' Hara-Veintimilla5
1Department of Neurology, Clínica Universidad de Navarra, Pamplona, Navarra, Spain.
Summary
Stronger muscles are linked to better cognitive health in aging. Maintaining good physical condition can slow cognitive decline and protect against impairment.
Area of Science:
- Gerontology
- Neuroscience
- Exercise Science
Background:
- Muscular function is crucial for healthy aging.
- Cognitive decline is a significant concern in older adults.
- The link between physical condition and cognitive trajectory requires further investigation.
Purpose of the Study:
- To examine the relationship between baseline muscle condition and cognitive performance changes over two years.
- To determine if physical performance predicts cognitive evolution in older adults.
Main Methods:
- Observational analysis of longitudinal data from the control arm of the FINGER trial (n=583).
- Baseline physical performance assessed via gait speed, grip strength, and Short Physical Performance Battery (SPPB).
- Logistic regression models used to analyze associations between physical performance and cognitive score changes.
Main Results:
- Higher baseline chair stand performance, SPPB scores, and grip strength were associated with more favorable cognitive trajectories (global cognition, memory, executive function).
- These associations were particularly significant for memory.
- Gait speed did not show significant associations with cognitive changes.
Conclusions:
- Better initial physical condition is linked to more favorable cognitive evolution in aging.
- This highlights a strong connection between physical and cognitive health.
- Interventions targeting muscle health may impact brain health and protect against cognitive impairment in aging.
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