Related Experiment Video
Updated: Jan 13, 2026

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Biological Compatibility Profile on Biomaterials for Bone Regeneration
Published on: November 16, 2018
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Tartrate-Resistant Acid Phosphatase-Positive Cells: Putative Mediators of Peri-Implant Bone Healing
Nahrain Warda1, Ryan Noh1, J E Davies1,2
1Faculty of Dentistry, University of Toronto, Toronto, Ontario, Canada.
Journal of Periodontal Research
|January 7, 2026
Abstract:
A pre-clinical rabbit study shows peri-implant tissue contains mono- and multinucleate tartrate-resistant acid phosphatase (TRAP) + cells and a plethora of punctate extracellular TRAP staining. The latter provides a putative extracellular vesicular trafficking mechanism by which these cells drive early osseointegration.

