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Updated: Jan 13, 2026

Activation and Measurement of NLRP3 Inflammasome Activity Using IL-1β in Human Monocyte-derived Dendritic Cells
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Activation and Measurement of NLRP3 Inflammasome Activity Using IL-1β in Human Monocyte-derived Dendritic Cells

Published on: May 22, 2014

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UBE2O-mediated monoubiquitination licenses NLRP6 inflammasome activation in the intestine

Decai Wang1, Xuequn Chen1, Kaiwen Sui1

  • 1State Key Laboratory of Immune Response and Immunotherapy, Center for Advanced Interdisciplinary Science and Biomedicine of IHM, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei 230026, China.

Cell Host & Microbe
|January 7, 2026
PubMed

Keywords:
NLRP6UBE2Oconformational transitioncytoplasmic sequestrationinfectioninflammasomeinflammationmonoubiquitinationoligomerizationsteric hindrance

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