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Updated: May 6, 2026

A Methodological Approach to Non-invasive Assessments of Vascular Function and Morphology
Published on: February 7, 2015
Association between body roundness index and stroke: a cross-sectional study based on representative populations from
Ning Li1, Jiwei Sun1, Yesen Zhang1
1Department of Neurosurgery, The First Affiliated Hospital of Bengbu Medical University, Bengbu 233000, China.
Abstract:
Previous studies had confirmed an association between Body Roundness Index (BRI) and stroke, but it remains unclear whether this association holds across different countries and populations. This study aimed to investigate the association between BRI and stroke across different national cohorts. Data were obtained from the National Health and Nutrition Examination Survey (NHANES) from 2005 to 2018 and the English Longitudinal Study of Aging (ELSA) from 2012 to 2013, and multifactorial logistic regression models were used to assess the relationship between BRI and stroke. Moreover, restricted cubic spline (RCS) analysis, subgroup analysis, and Receiver Operating Curves (ROC) were also used. The study indicated that higher BRI levels were significantly associated with stroke. Participants in the highest BRI quartile (Q4) had a significantly association with stroke compared to those in the lowest quartile (Q1). ROC indicated that BRI demonstrated superior capability in identifying stroke compared to traditional indicators. Our findings implied that association between BRI and stroke validated in two independent national samples from the US and the UK, suggesting that BRI may have cross-national applicability as a stroke risk biomarker.
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