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Gregory A Merrell1

  • 1The Indiana Hand to Shoulder Center, 8501 Harcourt Road, Indianapolis, IN 46260.

The Journal of Hand Surgery
|January 7, 2026
PubMed
Abstract

No abstract available in PubMed .

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Joints form during embryonic development in conjunction with the formation and growth of the associated bones. The embryonic tissue that gives rise to all bones, cartilage, and connective tissues of the body is called mesenchyme.
The mesenchymal stem cells differentiate into chondrocytes that form the hyaline cartilage, and later the cartilaginous model of the bone. This model further transforms into a bone. This process is known as endochondral ossification.
During development, the limbs...