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Related Concept Videos

Prochirality02:05

Prochirality

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The concept of prochirality leads to the nomenclature of the individual faces of a molecule and plays a crucial role in the enantioselective reaction. It is a concept where two or more achiral molecules react to produce chiral products. A typical process is the reaction of an achiral ketone to generate a chiral alcohol. Here, the achiral reactant reacts with an achiral reducing agent, sodium borohydride, to generate an equimolar mixture of the chiral enantiomers of the product. For example, an...
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Molecules with Multiple Chiral Centers02:25

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Molecules that possess multiple chiral centers can afford a large number of stereoisomers. For instance, while some molecules like 2-butanol have one chiral center, defined as a tetrahedral carbon atom with four different substituents attached, several molecules like butane-2,3-diol have multiple chiral centers. A simple formula to predict the number of stereoisomers possible for a molecule with n chiral centers is 2n. However, there can be a lower number where some of the stereoisomers are...
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Chirality02:25

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Chirality is a term that describes the lack of mirror symmetry in an object. In other words, chiral objects cannot be superposed on their mirror images. For example, our feet are chiral, as the mirror image of the left foot, the right foot, cannot be superposed on the left foot.
Chiral objects exhibit a sense of handedness when they interact with another chiral object. For example, our left foot can only fit in the left shoe and not in the right shoe. Achiral objects — objects that have...
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Chair Conformation of Cyclohexane02:02

Chair Conformation of Cyclohexane

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The chair conformation is the most stable form of cyclohexane due to the absence of angle and torsional strain. The absence of angle strain is a result of cyclohexane’s bond angle being very close to the ideal tetrahedral bond angle of 109.5° in its chair conformer. Similarly, the torsional strain is also absent owing to the perfectly staggered arrangement of bonds.
The hydrogen atoms linked to carbons are arranged in two different axial and equatorial orientations to achieve this...
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Radicals: Electronic Structure and Geometry01:07

Radicals: Electronic Structure and Geometry

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This lesson delves into the geometry of a radical, which is influenced by the electronic structure of the molecule. The principle is similar to that of a lone pair, where the unpaired electron influences the geometry at the radical center.
Accordingly, the structure of a trivalent radical lies between the geometries of carbocations and carbanions. An sp2-hybridized carbocation is trigonal planar, while an sp3-hybridized carbanion is trigonal pyramidal. Here, the difference in geometry is...
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Stereoisomerism of Cyclic Compounds02:33

Stereoisomerism of Cyclic Compounds

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In this lesson, we delve into the role of ring conformation and its stability, which determines the spatial arrangement and, consequently, the molecular symmetry and stereoisomerism of cyclic compounds. 1,2-Dimethylcyclohexane is used as a case study to evaluate the possible number of stereoisomers. Here, given the multiple (n = 2) chiral centers, there are 2n = 4 possible configurations that lack a plane of symmetry, as the ring skeleton exists in a non-planar chair conformation. In addition,...
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Microfluidic-based Synthesis of Covalent Organic Frameworks COFs: A Tool for Continuous Production of COF Fibers and Direct Printing on a Surface
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Topology-Controlled Chirality and Spin Selectivity in Two-Dimensional Covalent Organic Frameworks.

Chao Jiang1, Chuanyu Jin2, Yao Lv3

  • 1School of Chemistry and Chemical Engineering and State Key Laboratory of Metal Matrix Composites, Shanghai Jiao Tong University, Shanghai 200240, China.

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Topological isomerism in 2D covalent organic frameworks (COFs) enables tunable spin polarization for spintronics. The

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Area of Science:

  • Materials Science
  • Condensed Matter Physics
  • Organic Chemistry

Background:

  • Electron spin control is crucial for spintronics, with the chirality-induced spin selectivity (CISS) effect enabling spin-polarized transport.
  • Achieving robust and tunable spin polarization in solid-state materials is a significant challenge.

Purpose of the Study:

  • To investigate topological isomerism as a strategy to modulate chirality and spin selectivity in 2D covalent organic frameworks (COFs).
  • To synthesize and characterize two distinct chiral COFs (TPE-KGM and TPE-SQL) with different network topologies (kgm and sql).

Main Methods:

  • Synthesis of two Zn(salen)-based chiral COFs (TPE-KGM and TPE-SQL) from identical precursors.
  • Characterization using circular dichroism (CD) and circularly polarized luminescence (CPL) to assess chiral amplification.
  • Magnetic conductive atomic force microscopy (mc-AFM) to measure spin polarization.
  • Fabrication of van der Waals heterostructures with WSe2 for spin injection studies.

Main Results:

  • The sql topology COF exhibited long-range structural chirality and enhanced spin selectivity (83% polarization) compared to the kgm topology COF (53% polarization).
  • CD and CPL measurements confirmed stronger chiral amplification in the sql topology.
  • Spin injection into WSe2 heterostructures showed higher circular polarization for TPE-SQL (8.1%) than TPE-KGM (3.9%) at 78 K.

Conclusions:

  • Topological isomerism in 2D COFs provides a direct route to control chirality and spin selectivity.
  • This approach advances the design of chiral optoelectronic and valleytronic materials for spintronic applications.