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Updated: Jan 13, 2026

Urinary Bladder Distention Evoked Visceromotor Responses as a Model for Bladder Pain in Mice
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Urobiome Analysis in Interstitial Cystitis/Bladder Pain Syndrome Reveals Nuanced Differences Associated with

Seth Reasoner, Jamisha Francis, Mollie Gidney

    Biorxiv : the Preprint Server for Biology
    |January 8, 2026
    PubMed
    Summary

    The study found no widespread urobiome differences in interstitial cystitis/bladder pain syndrome (IC/BPS) patients based on pain localization. However, specific bacterial changes, like reduced Dialister, were linked to localized pelvic pain in IC/BPS.

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