Related Experiment Video

Updated: Jan 13, 2026

Generation of a Novel Dendritic-cell Vaccine Using Melanoma and Squamous Cancer Stem Cells
12:43

Generation of a Novel Dendritic-cell Vaccine Using Melanoma and Squamous Cancer Stem Cells

Published on: January 6, 2014

12.2K

Neoantigen dendritic cell vaccination combined with conventional chemotherapy for a patient with advanced transverse

Hideya Onishi1,2,3, Atsushi Higa1,2, Mayu Tasaki1,2

  • 1Osaka Iseikai Cancer and Neurological Intractable Disease Treatment Clinic, 2-9-15-8F Higashinakajima, Higashiyodogawa-ku, Osaka, 533-0033, Japan.

Journal of Surgical Case Reports
|January 8, 2026
PubMed

Insights

Neoantigen dendritic cell (DC) vaccination shows promise in personalized cancer immunotherapy. This approach helped a colon cancer patient achieve disease-free survival, indicating its potential role in immune surveillance against cancer recurrence.

Area of Science:

  • Oncology
  • Immunotherapy
  • Genomics

Background:

  • Neoantigen dendritic cell (DC) vaccination is a personalized cancer immunotherapy.
  • Genomic analysis guides neoantigen identification for targeted therapies.
  • Further data on neoantigen DC vaccination efficacy is needed.
Keywords:
advanced colon cancerclass I antigencytotoxic T celldendritic cell vaccinationneoantigen

More Related Videos

Experimental Melanoma Immunotherapy Model Using Tumor Vaccination with a Hematopoietic Cytokine09:15

Experimental Melanoma Immunotherapy Model Using Tumor Vaccination with a Hematopoietic Cytokine

Published on: February 24, 2023

3.9K
Preparation of Tumor Antigen-loaded Mature Dendritic Cells for Immunotherapy08:40

Preparation of Tumor Antigen-loaded Mature Dendritic Cells for Immunotherapy

Published on: August 1, 2013

18.6K

Related Concept Videos

Cancer Vaccines01:30

Cancer Vaccines

Cancer treatment vaccines are a rapidly evolving field that offers a promising approach to immunotherapy. Unlike traditional vaccines that prevent diseases, cancer treatment vaccines are designed to treat existing cancers by stimulating the immune system to recognize and attack cancer cells.
Cancer vaccines come in two categories: preventive (prophylactic) and treatment (active). Preventive vaccines, such as the Human Papillomavirus (HPV) vaccine, protect against viruses that cause certain...
946
Tumor Immunotherapy01:27

Tumor Immunotherapy

Immunotherapy is a treatment that boosts or manipulates the immune system to fight diseases, including cancer. For instance, by stimulating an immune response through vaccinations against viruses that cause cancers, like hepatitis B virus and human papillomavirus, these diseases can be prevented. Nonetheless, some cancer cells can avoid the immune system due to their rapid mutation and division. The immune response to many cancers involves three phases: elimination, equilibrium, and escape.
1.7K
Chemotherapy-Induced Nausea and Vomiting: Neurokinin-1 Receptor Antagonists01:28

Chemotherapy-Induced Nausea and Vomiting: Neurokinin-1 Receptor Antagonists

Neurokinin 1 (NK1) receptors are distributed across the GI tract, vagal afferents, and key CNS regions including the central vomiting center and chemoreceptor trigger zone (CTZ) Chemotherapy agents stimulate enterochromaffin cells in the gastrointestinal (GI) tract to release large amounts of substance P (SP). SP is a neuropeptide released by specific sensory nerves in response to many different stressors, including those in the GI mucosa affected by chemotherapy.  SP binds and activates...
564