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Targeted Muscle Reinnervation to Lumbrical Muscles for Symptomatic Digital Stump Neuroma: Surgical Technique
Olga Politikou1, Michael A Wirth1, Martina Greminger1
1From the Division of Plastic Surgery and Hand Surgery, University Hospital Zurich, Zurich, Switzerland.
Plastic and Reconstructive Surgery. Global Open
|January 8, 2026
Summary
Targeted muscle reinnervation (TMR) offers a new approach to treating stump neuromas by redirecting nerve growth. This surgical technique may prevent neuroma recurrence, improving patient outcomes.
Area of Science:
- Surgical innovation
- Neurology
- Regenerative medicine
Background:
- Symptomatic stump neuromas are a common complication of amputation.
- Traditional treatments for neuromas are often passive and may not prevent recurrence.
Purpose of the Study:
- To detail the surgical technique of applying Targeted Muscle Reinnervation (TMR) to the lumbrical muscles.
- To provide a reproducible method for TMR in treating stump neuromas.
Main Methods:
- Surgical procedure description for TMR applied to lumbrical muscles.
- Inclusion of detailed graphic, photographic, and video illustrations.
- Focus on ensuring surgical reproducibility.
Main Results:
- The study successfully detailed the TMR surgical steps for lumbrical muscle application.
- Illustrative materials were provided to aid in understanding and replication.
Conclusions:
- Targeted Muscle Reinnervation (TMR) is a viable surgical advancement for treating symptomatic stump neuromas.
- The described technique and illustrations aim to facilitate reproducible application of TMR, potentially reducing neuroma recurrence.

