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Developing a smart and scalable tool for histopathological education-PATe 2.0.

Lina Winter1, Annalena Artinger1, Hendrik Böck1

  • 1Institute of Pathology, University Medical Centre Mannheim, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.

Journal of Pathology Informatics
|January 8, 2026
PubMed
Summary

PATe 2.0 enhances pathology education with a scalable, web-based digital microscopy platform. This redeveloped system offers improved usability, faster image processing, and greater flexibility for educational and research applications.

Keywords:
Artificial intelligence integrationDigital pathologyInteractive learningMedical educationMicroservices architectureScalabilityUser-centric designVirtual microscopeWhole-slide imaging (WSI)

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Area of Science:

  • Digital pathology
  • Medical education technology

Background:

  • Digital microscopy is vital for pathology education, offering scalable and standardized learning resources.
  • Previous systems like PATe (2015) provided foundational digital microscopy capabilities.

Purpose of the Study:

  • To redevelop and enhance the PATe system into PATe 2.0, a scalable web-application for digital microscopy in pathology education.
  • To improve usability, performance, and flexibility for pathology education and research.

Main Methods:

  • Agile, iterative development process utilizing a microservices architecture.
  • Integration of a modern, responsive web-based user interface for desktop and tablet use.
  • Automation of whole-slide image uploads and processing, supporting open formats (DICOM, OpenSlide).

Main Results:

  • PATe 2.0 demonstrates significantly reduced tile request times compared to the original PATe system.
  • The platform ensures modularity, scalability, and reliability through its microservices architecture.
  • Enhanced interoperability and adaptability across different institutions due to open format support.

Conclusions:

  • PATe 2.0 offers a robust digital microscopy solution, improving usability, performance, and flexibility in pathology education.
  • The platform's design facilitates future integration of research algorithms.
  • PATe 2.0 is a pivotal tool for advancing pathology education and research through digital microscopy.