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Related Concept Videos

Clamper Circuit01:14

Clamper Circuit

966
A clamper circuit, also known as a DC restorer, represents a specialized variant of the rectifier circuit, notable for its method of taking the output across the diode rather than the capacitor. This configuration lends to several distinctive applications, particularly in handling square wave inputs.
Within this circuit, the diode's orientation prompts the capacitor to charge up to the level of the most negative peak of the input signal. Upon reaching this state, the diode ceases to...
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Production Efficiency01:01

Production Efficiency

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Net production efficiency (NPE) is the efficiency at which organisms assimilate energy into biomass for the next trophic level. Due to low metabolic rates and less energy spent on thermoregulatory processes, the NPE of ectotherms (cold-blooded animals) is 10 times higher than endotherms (warm-blooded animals).
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Updated: Jan 13, 2026

A Method for Investigating Change Blindness in Pigeons Columba Livia
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PCORnet®: 10 Years of Research Innovation.

Lauren W Cohen1, Rowena J Dolor2, Mark Weiner3

  • 1Duke Clinical Research Institute, Durham, NC.

Medical Care
|January 8, 2026
PubMed
Summary
This summary is machine-generated.

The Patient-Centered Outcomes Research Network (PCORnet) infrastructure supports large-scale clinical research, analyzing data from over 47 million patients in 2023 to identify common conditions and social determinants of health.

Keywords:
networkspatient-centricityreal-world data

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Area of Science:

  • Health Services Research
  • Clinical Informatics
  • Public Health

Background:

  • Established in 2014 by PCORI, PCORnet® facilitates clinical trials and patient-centered research.
  • Focuses on generating knowledge to improve healthcare and patient outcomes.
  • Summarizes decade-long achievements and recent progress of the PCORnet® infrastructure.

Purpose of the Study:

  • To provide an update on the expanded patient population within PCORnet® Clinical Research Networks (CRNs).
  • To share priorities for the future development and utilization of the PCORnet® infrastructure.
  • To analyze common health conditions and social deprivation within the PCORnet® patient population.

Main Methods:

  • Queried electronic health records from 71 PCORnet® CRN participating health systems (as of July 2024).
  • Analyzed data to describe 10 common health conditions.
  • Stratified findings by age, sex, race, ethnicity, and social deprivation index.

Main Results:

  • Over 47 million unique patients had encounters in 2023 across participating health systems.
  • Most common conditions: hypertension (18%), anxiety disorders (10%), type 2 diabetes (8%), asthma (5%).
  • More than 20% of patients were in the top 50% for area deprivation metrics; 51 studies supported, meeting CDM, engagement, and results return guidelines.

Conclusions:

  • PCORnet® CRNs encompass diverse, growing patient populations, including socioeconomic data.
  • Continued community and patient engagement, alongside national research, can improve care for various conditions.
  • The PCORnet® infrastructure is vital for advancing health outcomes through large-scale, patient-centered research.