Related Experiment Video
Updated: Jan 13, 2026

Author Spotlight: Assessing Surgical Frailty with Point-of-Care Ultrasound of Quadriceps Muscles
Published on: July 26, 2024
The association between hyperkyphosis and physical function in geriatric outpatients with frailty
Marije C Koelé1,2,3, Nathalie van der Velde4,5, Jos P C M van Campen6
1Amsterdam UMC location University of Amsterdam, Department of Internal Medicine, Division of Geriatrics, Meibergdreef 9, Amsterdam, 1105 AZ, the Netherlands. m.c.koele@amsterdamumc.nl.
None:
Currently, it is unknown whether hyperkyphosis is associated with lower physical function in older persons with frailty, who have a high risk of functional decline. Hyperkyphosis was highly prevalent and independently associated with lower physical function. Early detection and treatment of hyperkyphosis may contribute to the preservation of physical function.
Purpose:
To investigate the association between hyperkyphosis and physical function in older persons with frailty, who have a high risk of functional decline METHODS: Hyperkyphosis was defined as a Cobb angle ≥ 50°, ≥ 3.4 cm of blocks or an occiput-to-wall distance of ≥ 5.0 cm. The association with physical function (Timed Up and Go Test, Short Physical Performance Battery, Berg Balance Scale, and hand grip strength) was assessed through multifactorial regression analyses.
Results:
Hyperkyphosis was highly prevalent in the cohort (n = 337, mean age 80.0 ± 7.9 years) with a prevalence ranging from 43 to 84%, depending on which measurement method was used. Hyperkyphosis was independently associated with a longer Timed Up and Go time and a lower Berg Balance Scale score, only when kyphosis was measured with the blocks method (Timed Up and Go: adjusted OR 3.86, 95% CI 1.50-9.91; Berg Balance Scale: adjusted OR 9.42, 95% CI 2.27-39.12). Hyperkyphosis was not associated with Short Physical Function Battery or hand grip strength.
Conclusion:
Hyperkyphosis was highly prevalent and independently associated with the Timed Up and Go test and Berg Balance Scale, even in this population of geriatric outpatients with frailty and multimorbidity, thereby more at risk for functional decline. Early detection and treatment of hyperkyphosis may contribute to the preservation of physical function.
More Related Videos
05:53Measuring Frailty in HIV-infected Individuals. Identification of Frail Patients is the First Step to Amelioration and Reversal of Frailty
Published on: July 24, 2013
07:27Exergaming in Older People Living with HIV Improves Balance, Mobility and Ameliorates Some Aspects of Frailty
Published on: October 6, 2016
Related Concept Videos
Pharmacodynamics in Geriatric Patients: Effects of Age
Bone Disorders
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
Drug Dosing: Geriatric Patients
Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Distribution
Changes in the Appendicular Skeleton with Age
Initially, the limb buds consist of a core of mesenchyme covered by a layer of ectoderm. The ectoderm at the end of the limb bud thickens to form a narrow crest called the apical ectodermal ridge. This ridge stimulates the underlying...
Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Metabolism