Related Experiment Video
Updated: Jan 13, 2026

Augmenting Large Language Models via Vector Embeddings to Improve Domain-Specific Responsiveness
Published on: December 6, 2024
Intervention in Health Misinformation Using Large Language Models for Automated Detection, Thematic Analysis, and
Samira Malek1, Christopher Griffin2,3, Robert D Fraleigh2
1Department of Computer Science and Engineering, Pennsylvania State University, University Park, PA, United States.
Background:
The rapid growth of social media as an information channel has enabled the swift spread of inaccurate or false health information, significantly impacting public health. This widespread dissemination of misinformation has caused confusion, eroded trust in health authorities, led to noncompliance with health guidelines, and encouraged risky health behaviors. Understanding the dynamics of misinformation on social media is essential for devising effective public health communication strategies.
Objective:
This study aims to present a comprehensive and automated approach that leverages large language models (LLMs) and machine learning techniques to detect misinformation on social media, uncover the underlying causes and themes, and generate refutation arguments, facilitating control of its spread and promoting public health outcomes by inoculating people against health misinformation.
Methods:
We use 2 datasets to train 3 LLMs, namely, BERT, T5, and GPT-2, to classify documents into 2 categories: misinformation and nonmisinformation. In addition, we use a separate dataset to identify misinformation topics. To analyze these topics, we applied 3 topic modeling algorithms-Latent Dirichlet Allocation, Top2Vec, and BERTopic-and selected the optimal model based on performance evaluated across 3 metrics. Using a prompting approach, we extract sentence-level representations for the topics to uncover their underlying themes. Finally, we design a prompt text capable of identifying misinformation themes effectively.
Results:
The trained BERT model demonstrated exceptional performance, achieving 98% accuracy in classifying misinformation and nonmisinformation, with a 44% reduction in false-positive rates for artificial intelligence-generated misinformation. Among the 3 topic modeling approaches used, BERTopic outperformed the others, achieving the highest metrics with a Coherence Value of 0.41, Normalized Pointwise Mutual Information of -0.086, and Inverse Rank-Biased Overlap of 0.99. To address the issue of unclassified documents, we developed an algorithm to assign each document to its closest topic. In addition, we proposed a novel method using prompt engineering to generate sentence-level representations for each topic, achieving a 99.6% approval rate as "appropriate" or "somewhat appropriate" by 3 independent raters. We further designed a prompt text to identify themes of misinformation topics and developed another prompt capable of detecting misinformation themes with 82% accuracy.
Conclusions:
This study presents a comprehensive and automated approach to addressing health misinformation on social media using advanced machine learning and natural language processing techniques. By leveraging LLMs and prompt engineering, the system effectively detects misinformation, identifies underlying themes, and provides explanatory responses to combat its spread. The proposed method was tested on an English language COVID-19-related dataset and has not been evaluated on real-world online social media data; the experiments were conducted offline.
More Related Videos
05:47Evidence-based Knowledge Synthesis and Hypothesis Validation: Navigating Biomedical Knowledge Bases via Explainable AI and Agentic Systems
Published on: June 13, 2025
05:56Objectification of Tongue Diagnosis in Traditional Medicine, Data Analysis, and Study Application
Published on: April 14, 2023
Related Concept Videos
Steps in Outbreak Investigation
Immune Response Against Viral Pathogens
NK Cells
NK cells are a crucial part of our innate immune system, acting as the first line of defense against viral infections. These cells can recognize and kill infected cells without prior exposure to the virus, effectively slowing down the spread of infection. Additionally, NK cells produce proinflammatory...
Microorganisms in Medicine and Therapeutics
Models of Health Promotion and Illness Prevention II
The agent-host-environment model states that disease results...
Healthcare Associated Infections II: Preventive Measures
The best practices for preventing healthcare-associated infections include hand hygiene, patient risk...
Vaccinations