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Updated: Jan 13, 2026

Monitoring Astrocyte Reactivity and Proliferation in Vitro Under Ischemic-Like Conditions
Published on: October 21, 2017
How astrocytes regulate microglia in CNS injury: BST2-high astrocytes at the border
1Center for Vascular Research, Institute for Basic Science (IBS), Daejeon, Republic of Korea; Department of Biological Sciences, Korea Advanced Institute of Science and Technology, Daejeon, Republic of Korea.
Abstract:
In this issue of Neuron, Zhang et al.1 identified a subset of BST2-high astrocytes that emerge at the ischemic injury border and promote microglial recruitment through the C3-C3aR pathway. These findings highlight BST2 as a key modulator of astrocyte-microglia communication and a potential therapeutic target for CNS injury.
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