Performance and safety of single-balloon enteroscopy and double-balloon enteroscopy for small-bowel disorders in children: a systematic review and meta-analysis
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View abstract on PubMed
Summary
This summary is machine-generated.Single-balloon enteroscopy (SBE) and double-balloon enteroscopy (DBE) show promise for pediatric small-bowel disorders. However, pediatric procedures have lower complete enteroscopy rates, shallower insertion, and higher adverse events than adult procedures.
Area Of Science
- Gastroenterology
- Pediatric Endoscopy
- Minimally Invasive Procedures
Background
- Balloon enteroscopy, including single-balloon enteroscopy (SBE) and double-balloon enteroscopy (DBE), is established for adult small-bowel diseases.
- Pediatric application of balloon enteroscopy presents unique challenges due to anatomical differences, with uncertain performance and safety outcomes.
Purpose Of The Study
- To evaluate the efficacy and safety of SBE and DBE in pediatric patients with small-bowel disorders.
- To compare pediatric balloon enteroscopy outcomes with existing adult data.
Main Methods
- A comprehensive literature search identified studies on SBE and DBE in pediatric small-bowel disorders.
- A univariate random-effects meta-analysis was conducted on data from 24 studies (1463 patients).
- Primary outcomes included diagnostic yield, therapeutic yield, and adverse event incidence.
Main Results
- Pooled diagnostic yield was 0.72, therapeutic yield 0.61, and overall adverse event rate 5.50%.
- DBE achieved greater depth of maximal insertion and a higher complete enteroscopy rate than SBE.
- Pediatric procedures showed lower complete enteroscopy rates (0.10) and shallower insertion compared to adult data.
Conclusions
- Both SBE and DBE appear safe and effective for pediatric small-bowel disorders.
- Pediatric balloon enteroscopy outcomes differ from adults, with shallower insertion, lower complete enteroscopy rates, and higher adverse events.
- Findings are preliminary due to low certainty of evidence, requiring further standardized research.
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