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Evaluation of Chitosan (Axiostat®) as a Pulpotomy Agent in Primary Molars: An In Vivo Study
Nidhish Krishna1, Kavita Rai1, R Manju1
1Department of Pediatric and Preventive Dentistry, AB Shetty Memorial Institute of Dental Sciences, NITTE (Deemed to be University), Mangaluru, Karnataka, India.
Background:
In primary teeth, pulpotomy is a well-established intervention for managing cariously exposed coronal pulp, with formocresol long considered the gold-standard medicament. Recent research focuses on wound-healing phenomena and the use of regenerative materials like chitosan owing to its functional versatility and unique characteristics.
Aim:
To assess the clinical and radiographic outcomes of using chitosan as a pulpotomy agent in primary molars.
Materials And Methods:
Children aged 4-9 years, free from systemic illnesses and in need of pulpotomy, were selected. About 50 teeth were assigned to two groups: group I (chitosan) and group II (formocresol), and all treated teeth received stainless-steel crowns. Clinical and radiographic parameters were assessed at 1, 3, and 6 months posttreatment. The Chi-squared test was applied to compare the parameters and analyze the differences between the groups at the various time intervals.
Results:
Group I (chitosan) demonstrated a clinical and radiographic success rate of 95.6%, while group II (formocresol) achieved 100%. The variation between the groups was not statistically significant.
Conclusion:
The study indicated that chitosan (Axiostat®) can be considered a reliable pulpotomy agent in primary dentition and an effective substitute for formocresol.
How To Cite This Article:
Krishna N, Rai K, Manju R, et al. Evaluation of Chitosan (Axiostat®) as a Pulpotomy Agent in Primary Molars: An In Vivo Study. Int J Clin Pediatr Dent 2025;18(S-1):S61-S65.
