Bioactive glass-based core-shell nanoparticles: Multifunctional platforms for controlled drug release and biomedical applications
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View abstract on PubMed
Summary
This summary is machine-generated.Core-shell nanoparticles with bioactive glass cores offer advanced biomedical applications. These engineered nanomaterials provide tunable drug release and enhanced biological performance for next-generation therapies.
Area Of Science
- Biomaterials Science
- Nanotechnology
- Materials Chemistry
Background
- Core-shell nanoparticles are multifunctional platforms for precise control in biomedical applications.
- Bioactive glasses offer advantages over silica due to bioactivity and therapeutic ion release.
Purpose Of The Study
- To comprehensively review core-shell nanostructures with bioactive glass cores.
- To analyze shell materials for controlled release and biological performance.
Main Methods
- Discussed composition and synthesis of bioactive glass nanoparticles.
- Evaluated inorganic and polymeric shell materials for physicochemical roles.
- Explored challenges and future directions for clinical implementation.
Main Results
- Shell materials modulate drug diffusion, stability, degradation, and targeting.
- Bioactive glass core-shell structures offer tunable properties for tailored therapies.
- Inorganic, natural, and synthetic polymeric shells provide versatile engineering options.
Conclusions
- Core-shell bioactive glass nanoparticles represent a customizable strategy for advanced biomedical therapies.
- Surface engineering integrates structural functionalities for next-generation treatments.
- Addressing challenges in in vivo assays and clinical translation is crucial for implementation.
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