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Updated: Jan 13, 2026

Chemiluminescence-based Assays for Detection of Nitric Oxide and its Derivatives from Autoxidation and Nitrosated Compounds

Chemiluminescence-based Assays for Detection of Nitric Oxide and its Derivatives from Autoxidation and Nitrosated Compounds

Published on: February 16, 2022

Optical Sensing Techniques for Nitrite Detection: A Comprehensive Review and Future Perspectives.

Yihong Huang¹, Na Liao¹, Haojie Wang¹

¹Jiangxi Provincial Key Laboratory of Tissue Engineering; Key Laboratory of Biomedical Sensors of Ganzhou; School of Pharmacy; School of Medical and Information Engineering; Scientific Research Center, Gannan Medical University, Ganzhou, China.

Comprehensive Reviews in Food Science and Food Safety

|January 9, 2026

Summary

Accurate nitrite (NO2-) detection is crucial for food safety. Optical sensing offers sensitive methods, but challenges in selectivity and real-world application require further research for reliable food quality monitoring.

Keywords:

challenges detection food nitrite optical sensing technique

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Published on: December 25, 2016

Area of Science:

Analytical Chemistry
Food Science
Environmental Science

Background:

Nitrite (NO2-) is vital in food but poses health risks.
Accurate quantitative detection of nitrite is essential for safety and research.
Optical sensing is a promising technology for rapid and sensitive nitrite detection.

Purpose of the Study:

To systematically review optical sensing techniques for nitrite detection in food.
To highlight recent advancements and challenges in nitrite analysis using optical methods.
To explore solutions and future research directions for improved nitrite detection.

Main Methods:

Review of ultraviolet-visible absorption spectroscopy/colorimetry.
Review of fluorescence spectroscopy.
Review of surface-enhanced Raman spectroscopy, chemiluminescence, and electrochemiluminescence.

Main Results:

Optical sensing techniques show high sensitivity and rapid response for nitrite detection.
Multimodal approaches enhance detection capabilities.
Current methods face challenges in anti-interference, sensitivity-selectivity balance, and real-sample applicability.

Conclusions:

Optical sensing technology has advanced significantly for nitrite detection.
Addressing challenges is critical for practical application in food quality monitoring.
Further research is needed to provide robust technical support for food safety.