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Multi-omics and perturbation screens as discovery tools in immunometabolism

Nicole M Chapman1, Hongbo Chi1

  • 1Department of Immunology, St Jude Children's Research Hospital, Memphis, Tennessee, United States of America.

Plos Biology
|January 9, 2026
PubMed

Metabolic rewiring of immune cells has broad impacts on immune responses and disease outcomes. Systems biology approaches, such as multi-omics profiling and perturbation screening, could uncover new actionable targets and therapeutic avenues to explore.

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