A concise overview of mammalian spermatogenesis

Tasrin Sultana1, Peter Sutovsky1,2

  • 1Division of Animal Sciences, University of Missouri, Columbia, MO, USA.

Summary

Spermatogenesis is a complex process producing mature spermatozoa essential for male fertility. This study overviews testis organization, sperm structure, and the regulation of spermatogenesis for reproductive success.

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Spermatogenesis01:41

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Spermatogenesis is the process by which haploid sperm cells are produced in the male testes. It starts with stem cells located close to the outer rim of seminiferous tubules. These spermatogonial stem cells divide asymmetrically to give rise to additional stem cells (meaning that these structures “self-renew”), as well as sperm progenitors, called spermatocytes. Importantly, this method of asymmetric mitotic division maintains a population of spermatogonial stem cells in the male...
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Spermatogenesis01:22

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Spermatogenesis is a complex process that involves the development of sperm cells from undifferentiated stem cells in the seminiferous tubules of the testes. The process is essential for the production of mature and functional sperm cells that are capable of fertilizing an egg.
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