Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Electrical Power01:07

Electrical Power

Electric power is the product of current and voltage, represented in units of joules per second, or watts. For example, cars often have one or more auxiliary power outlets with which you can charge a cell phone or other electronic devices. These outlets may be rated at 20 amps and 12 volts, so that the circuit can deliver a maximum power of 240 watts. Consider a 25 Watt bulb and a 60 Watt bulb. The conversion of electrical energy produces heat and light, while the kinetic energy lost by the...
Electric Generator: Alternator01:25

Electric Generator: Alternator

Electric generators induce an emf by rotating a coil in a magnetic field. A simple alternator is an AC generator that creates electrical energy that varies sinusoidally with time. A simple alternator consists of a conducting loop that is placed inside a uniform magnetic field. The loop is connected to split rings connected to the external circuit with the help of brushes.
The magnetic flux passing through the coil varies sinusoidally as the loop rotates inside the magnetic field. This...
DC Generator01:19

DC Generator

An alternator converts mechanical energy into electrical energy that varies sinusoidally, resulting in AC current. Meanwhile, a DC generator converts mechanical energy into electrical energy, which are DC pulses with the same polarity. The construction of a DC generator is similar to that of an alternator, except that the pair of slip rings is replaced by a single split ring, also called a commutator. The commutator functions like a periodic rotary switch; it changes the contacts with the...
Electric Circuit Elements01:21

Electric Circuit Elements

Circuit elements are the basic building blocks of an electric circuit. Essentially, an electric circuit is the interconnection of these elements. Within electric circuits, one can find two types of elements: passive and active. Active elements have the ability to generate energy, whereas passive elements do not. Passive elements include components like resistors, capacitors, and inductors, while active elements typically encompass generators, batteries, and operational amplifiers.
The most...
Electrical Systems01:21

Electrical Systems

In electrical engineering, the analysis of networks composed of passive linear components — resistors (R), capacitors (C), and inductors (L) — is fundamental. These components are organized into circuits where the relationship between input and output can be analyzed using transfer functions. The transfer function of an RLC circuit, which relates the voltage across a capacitor to the input voltage, can be derived using Kirchhoff's laws.
To derive the transfer function, consider an RLC circuit...
Electro-mechanical Systems01:19

Electro-mechanical Systems

Electromechanical systems are intricate configurations that effectively combine electrical and mechanical elements to achieve a desired outcome. Central to many of these systems is the DC motor, a device that converts electrical energy into mechanical motion, enabling various applications ranging from simple fans to complex robotic mechanisms.
A key component of the DC motor is the armature, a rotating circuit positioned within a magnetic field. As an electric current passes through the...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Nonaqueous Ion Transport through Nanopores: A Nonlinear Behavior Driven by Enhanced Ion Correlation.

Journal of the American Chemical Society·2026
Same author

Local cation-clamping distorts and softens RNA duplex.

Communications biology·2026
Same author

A universal entropic pulling force caused by binding.

Nature communications·2025
Same author

Spatially Resolved Mapping of Voltage-Gated Proton Channel Activity Reveals Delayed Proton Transport in Local Microenvironments.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)·2025
Same author

A single-nanoprobe-integrated multi-modal microscope (SNIM).

The Review of scientific instruments·2025
Same author

Magnetic Sensing of Ion Transport in a Single Nanopore.

Nano letters·2025
Same journal

Taphonomic analysis at Liang Bua reveals the behavioral and technological capabilities of <i>Homo floresiensis</i>.

Science advances·2026
Same journal

Targeting granule initiation and amyloplast structure to create giant starch granules in wheat.

Science advances·2026
Same journal

A meta-analysis of carbon losses and gains from tropical moist forest degradation and regeneration.

Science advances·2026
Same journal

Ancient DNA reveals elite dynastic rule among Iron Age Eurasian Steppe nomads.

Science advances·2026
Same journal

Targeting astrocytic Dp71 attenuates BBB disruption after traumatic brain injury through WTAP-associated m<sup>6</sup>A regulation of MMP2.

Science advances·2026
Same journal

Pancreatic α cells are required for nutrient homeostasis by regulating dynamic β cell networks in islets.

Science advances·2026
See all related articles

Related Experiment Video

Updated: Jul 4, 2026

Making Patch-pipettes and Sharp Electrodes with a Programmable Puller
05:30

Making Patch-pipettes and Sharp Electrodes with a Programmable Puller

Published on: October 8, 2008

25.9K

Programmable electric tweezers.

Yuang Chen1, Haojing Tan1, Jiahua Zhuang1

  • 1Laboratory of Experimental Physical Biology, Department of Chemistry, Zhejiang University, 310058 Hangzhou, China.

Science Advances
|January 9, 2026
PubMed
Summary
This summary is machine-generated.

We developed a programmable electric tweezer (PET) for precise, on-demand manipulation of single microscopic objects. This technology enables advanced control over electromagnetic fields for versatile single-molecule studies.

More Related Videos

Single-molecule Manipulation of G-quadruplexes by Magnetic Tweezers
08:28

Single-molecule Manipulation of G-quadruplexes by Magnetic Tweezers

Published on: September 19, 2017

8.6K
High-Speed Magnetic Tweezers for Nanomechanical Measurements on Force-Sensitive Elements
08:50

High-Speed Magnetic Tweezers for Nanomechanical Measurements on Force-Sensitive Elements

Published on: May 12, 2023

2.7K

Related Experiment Videos

Last Updated: Jul 4, 2026

Making Patch-pipettes and Sharp Electrodes with a Programmable Puller
05:30

Making Patch-pipettes and Sharp Electrodes with a Programmable Puller

Published on: October 8, 2008

25.9K
Single-molecule Manipulation of G-quadruplexes by Magnetic Tweezers
08:28

Single-molecule Manipulation of G-quadruplexes by Magnetic Tweezers

Published on: September 19, 2017

8.6K
High-Speed Magnetic Tweezers for Nanomechanical Measurements on Force-Sensitive Elements
08:50

High-Speed Magnetic Tweezers for Nanomechanical Measurements on Force-Sensitive Elements

Published on: May 12, 2023

2.7K

Area of Science:

  • Biophysics
  • Nanotechnology
  • Electrical Engineering

Background:

  • Single-object manipulation using electromagnetic fields is crucial for applications like optical and magnetic traps.
  • Achieving function-on-demand manipulation requires sophisticated, local control over electromagnetic fields, which is currently challenging.

Purpose of the Study:

  • To introduce a novel concept of programmable single-object manipulation using a programmable electric tweezer (PET).
  • To enable function-on-demand control of electromagnetic fields for manipulating microscopic objects.

Main Methods:

  • Developed a programmable electric tweezer (PET) with a multibit electrode system featuring four individually addressed electrodes.
  • Integrated a probe-based electrode array for spatial-selective manipulation and adjustable electrode gaps for multiscale target handling.
  • Independently programmed electrical signals for each electrode to achieve multiscale, spatiotemporal control and in situ measurements using multiple electric principles.

Main Results:

  • Demonstrated spatial-selective and multiscale manipulation capabilities of the PET system.
  • Achieved function-on-demand single-object manipulation, moving beyond function-fixed approaches.
  • Successfully measured the spontaneous relaxation of DNA supercoiling using the PET's integrated functions, showcasing its versatility.

Conclusions:

  • The programmable electric tweezer (PET) represents a significant advancement in single-object manipulation technology.
  • PET enables unprecedented control over electromagnetic fields for versatile, on-demand manipulation of microscopic objects.
  • The system is highly effective for investigating stochastic biophysical phenomena at the single-molecule level.