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Efficacy differentiation of sterile faecal filtrates in Clostridioides difficile infection - Authors' reply

Dina Kao1, Huiping Xu2, Thomas Louie3

  • 1Division of Gastroenterology, Department of Medicine and Dentistry, University of Alberta, Edmonton, AB T6G 2P8, Canada.

The Lancet. Gastroenterology & Hepatology
|January 9, 2026
PubMed
Abstract

No abstract available in PubMed .

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Generic intravenous (IV) drugs are considered bioequivalent to their branded counterparts due to their 100% bioavailability upon administration. However, variations in stability among different drug products can significantly influence their therapeutic performance, even if they are pharmaceutically equivalent.Cefuroxime, a prophylactic antimicrobial, is often used as a single-dose IV injection for patients undergoing coronary artery bypass grafting surgery. A 3 g dose typically provides...
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