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Hypersensitivity Pneumonitis: Imaging Findings and Patterns.

Taylor Sellers¹, Maria Daniela Martin¹, Jeffrey P Kanne¹

¹Department of Radiology, University of Wisconsin School of Medicine and Public Health, Madison, WI.

Seminars in Roentgenology

|January 9, 2026

Summary

This summary is machine-generated.

This review highlights the critical role of CT imaging in diagnosing hypersensitivity pneumonitis, aligning with recent guidelines. It details imaging patterns for both nonfibrotic and fibrotic forms, aiding radiologists.

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Area of Science:

Radiology
Pulmonology
Medical Imaging

Background:

Recent guidelines emphasize CT imaging for hypersensitivity pneumonitis diagnosis.
Accurate CT interpretation is crucial for subsequent diagnostic steps.
Hypersensitivity pneumonitis presents variable CT findings, posing diagnostic challenges.

Purpose of the Study:

To review CT imaging features of hypersensitivity pneumonitis based on current guidelines.
To outline patterns of nonfibrotic and fibrotic hypersensitivity pneumonitis.
To provide radiologists with key information for diagnosis and differentiation.

Main Methods:

Review of current guidelines and classifications for hypersensitivity pneumonitis.
Summary of established and variable CT imaging features.
Discussion of differential diagnoses and related conditions.

Main Results:

CT analysis is integral to the multidisciplinary diagnosis of hypersensitivity pneumonitis.
Imaging features, though established, require careful characterization due to variability.
Key patterns for nonfibrotic and fibrotic hypersensitivity pneumonitis are presented.

Conclusions:

Radiologists must accurately identify and characterize CT findings for effective hypersensitivity pneumonitis diagnosis.
Understanding imaging patterns aids in differentiating hypersensitivity pneumonitis from other fibrotic lung diseases.
This review serves as a guide for interpreting CT scans in the context of hypersensitivity pneumonitis.