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Wearable devices for anxiety assessment: a systematic review
Mohamed Elgendi1,2, Karmen Markov3, Hangyu Liu3,4
1Department of Biomedical Engineering and Biotechnology, Khalifa University of Science and Technology, Abu Dhabi, UAE. mohamed.elgendi@ku.ac.ae.
Communications Medicine
|January 9, 2026
Summary
Wearable devices show promise for anxiety detection, with combined biosignals outperforming single signals. Multi-signal approaches achieved 81.94% accuracy, highlighting their clinical potential for mental health monitoring.
Area of Science:
- Biomedical Engineering
- Digital Health
- Psychophysiology
Background:
- Growing interest in wearable biosensors for anxiety disorder assessment.
- Electrocardiography (ECG) is a primary signal for cardiovascular monitoring.
- Respiratory, electrodermal activity (EDA), and photoplethysmography (PPG) also show potential.
Purpose of the Study:
- To systematically review and evaluate biosignals from wearable devices for anxiety detection.
- To compare the efficacy of individual versus combined signal approaches.
- To identify common features and classification methods used in anxiety detection.
Main Methods:
- Systematic review of 26 studies (2014-2024) using wearable device data for anxiety detection.
- Extraction of study design, signal types, features, classification methods, and accuracy.
- Calculation of pooled accuracies for single-signal and multi-signal strategies.
Main Results:
- Multi-signal approaches yielded higher pooled accuracy (81.94%) than single-signal approaches (76.85%).
- Electrocardiography (ECG) demonstrated the highest pooled accuracy (80.34%) as an individual signal.
- Common features included heart rate and heart rate variability (ECG), inspiratory-to-expiratory ratio (respiratory), skin conductance (EDA), and heart rate (PPG); Support Vector Machine was the main classifier.
Conclusions:
- Wearable devices possess significant clinical potential for anxiety detection.
- Multimodal biosignal approaches are more effective than single-signal methods.
- Future research should enhance algorithms, increase sample sizes, and validate in diverse settings.
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