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Mitral Stenosis I: Introduction01:22

Mitral Stenosis I: Introduction

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Mitral Valve Stenosis (MVS) is a heart condition where the mitral valve narrows, impeding blood circulation from the left atrium to the left ventricle. The etiology and pathophysiology of this condition are multifaceted, leading to a cascade of cardiovascular complications.Causes of Mitral Valve StenosisRheumatic Heart Disease: It is the main cause of mitral valve stenosis, particularly in developing nations. This condition arises from rheumatic fever, an inflammatory illness resulting from...
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Mitral Stenosis III: Medical Management01:26

Mitral Stenosis III: Medical Management

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Mitral stenosis, a condition marked by the narrowing of the mitral valve, necessitates an integrated approach for effective management. This approach includes preventative measures, medical therapy, and surgical interventions to reduce symptoms and prevent complications.PreventionPrevention of mitral stenosis primarily focuses on reducing the incidence of bacterial infections, particularly streptococcal infections, which can lead to rheumatic fever and subsequent valvular damage. Timely...
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Aortic Regurgitation I: Introduction01:15

Aortic Regurgitation I: Introduction

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IntroductionAortic regurgitation is characterized by the backward flow of blood from the aorta into the left ventricle during diastole and arises from the improper closure of the aortic valve. This condition results in left ventricular volume overload and can stem from both acute and chronic etiologies, each contributing uniquely to the disease's progression and symptomatology.Acute and Chronic CausesAcute aortic regurgitation often results from events that suddenly impair the integrity of the...
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Aortic Regurgitation III: Medical Management01:25

Aortic Regurgitation III: Medical Management

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Aortic regurgitation (AR) is when the aortic valve does not close or seal properly, leading to backward blood circulation from the aorta into the left ventricle during diastole. Common causes of AR include rheumatic heart disease, congenital valve defects, and aortic root dilation. Managing AR requires a multifaceted approach to alleviate symptoms, preserve left ventricular function, and address the underlying cause of the regurgitation. Patients with symptomatic AR or significant left...
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Mitral Valve Prolapse I: Introduction01:27

Mitral Valve Prolapse I: Introduction

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IntroductionThe mitral valve, one of the heart's four valves, regulates blood flow. These valves have flaps that open and close to direct blood properly through the heart and body. During each heartbeat, the flaps open for blood to pass through and seal shut to prevent backflow. Specifically, the mitral valve opens to allow blood flow from the heart's upper left chamber to the lower left chamber. It then closes securely as the lower left chamber contracts to pump blood to the body, preventing...
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Mitral Stenosis IV: Nursing Management01:27

Mitral Stenosis IV: Nursing Management

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A comprehensive nursing assessment is essential for patients with valvular heart disease, which involves any dysfunction of the heart valves that could impact blood flow and overall heart function.Subjective Data Collection:Chief Complaint and Present Illness: Start with the patient's primary concerns, focusing on the onset, duration, and progression of cardiac symptoms such as dyspnea, fatigue, chest pain, and palpitations.Past Medical History: Collect detailed information on any previous...
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  1. Home
  3. The Journey From Repair To Replacement In Pediatric Aortic Valve Stenosis: A 10-year Single-center Experience.
  1. Home
  3. The Journey From Repair To Replacement In Pediatric Aortic Valve Stenosis: A 10-year Single-center Experience.

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The journey from repair to replacement in pediatric aortic valve stenosis: a 10-year single-center experience.

Guowei Zeng1, Xinjie Zhang1, Longming Huang1

  • 1Department of Cardiothoracic Surgery, Shanghai Children's Medical Center, Shanghai Jiao Tong University School of Medicine, 1678 Dongfang Road, Shanghai, 200127, China.

BMC Pediatrics
|January 9, 2026

View abstract on PubMed

Summary
This summary is machine-generated.

Pediatric congenital aortic stenosis (AS) patients often need reoperation within 10 years of initial aortic valve (AoV) repair. AoV replacement during reoperation offers better long-term outcomes than repair for these children.

Keywords:
Aortic valve repairAortic valve replacementPediatric aortic valve stenosisReoperationRoss procedure

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Area of Science:

  • Pediatric Cardiology
  • Cardiovascular Surgery
  • Congenital Heart Disease

Background:

  • Congenital aortic stenosis (AS) requires timely intervention.
  • Long-term outcomes and reoperation strategies for pediatric AS after initial aortic valve (AoV) repair are not fully understood.

Purpose of the Study:

  • To evaluate reintervention outcomes and long-term prognosis in pediatric patients with isolated AS following their initial AoV repair.
  • To compare the effectiveness of different reoperation strategies.

Main Methods:

  • Retrospective analysis of clinical data from 203 pediatric patients with isolated AS who underwent initial AoV repair (2013-2024).
  • Primary outcome: freedom from reoperation.
  • Secondary outcomes: freedom from AoV replacement, freedom from moderate or greater AS/aortic regurgitation.

Main Results:

  • The 10-year freedom from AoV reoperation rate was 50.9%.
  • The 10-year freedom from AoV replacement rate was 62.7%.
  • AoV replacement during reoperation showed superior long-term outcomes compared to secondary AoV repair (P=0.001).

Conclusions:

  • Initial AoV repair for pediatric AS yields favorable outcomes, but nearly half of patients require reoperation within a decade.
  • AoV replacement is associated with better long-term quality of life for reoperations in pediatric AS patients.