Related Experiment Video

Updated: May 8, 2026

Establishing a Mouse Model of a Pure Small Fiber Neuropathy with the Ultrapotent Agonist of Transient Receptor Potential Vanilloid Type 1
09:39

Establishing a Mouse Model of a Pure Small Fiber Neuropathy with the Ultrapotent Agonist of Transient Receptor Potential Vanilloid Type 1

Published on: February 13, 2018

10.0K

Epimutation analysis reveals involvement of SLIT2/ROBO signaling pathway in painful diabetic neuropathy

Katarzyna Malgorzata Kwiatkowska1, Paolo Garagnani2,3, Francesca Ferraresi4

  • 1Department of Medical and Surgical Sciences (DIMEC), University of Bologna, 40126, Bologna, Italy. katarzyn.kwiatkowsk2@unibo.it.

Human Genomics
|January 10, 2026
PubMed

Keywords:
Biological agingDNA methylationDiabetic neuropathyEpigenetic driftEpivariantsNeuropathic painStochastic epigenetic mutations

More Related Videos

Modified Spared Nerve Injury Surgery Model of Neuropathic Pain in Mice04:34

Modified Spared Nerve Injury Surgery Model of Neuropathic Pain in Mice

Published on: January 25, 2022

6.6K
Partial Sciatic Nerve Ligation: A Mouse Model of Chronic Neuropathic Pain to Study the Antinociceptive Effect of Novel Therapies08:16

Partial Sciatic Nerve Ligation: A Mouse Model of Chronic Neuropathic Pain to Study the Antinociceptive Effect of Novel Therapies

Published on: October 6, 2022

7.6K

Related Concept Videos

Diabetic Neuropathy01:22

Diabetic Neuropathy

DefinitionDiabetic neuropathy is nerve damage caused by long-standing diabetes mellitus. It results directly from prolonged high blood sugar levels.PathophysiologyThe pathophysiology of diabetic neuropathy involves both metabolic and vascular disturbances triggered by chronic hyperglycemia.Metabolic injury: Elevated glucose levels activate the polyol pathway within nerve cells, leading to the accumulation of sorbitol and fructose. This increases oxidative stress, disrupts normal nerve...